lrp2b low density lipoprotein receptor-related protein 2b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: lrp2bprovided by ZNC
Official Full Name: low density lipoprotein receptor-related protein 2bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-111115-1
See related: Ensembl:ENSDARG00000007906 AllianceGenome:ZFIN:ZDB-GENE-111115-1
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary: Predicted to enable hormone binding activity. Predicted to be involved in receptor-mediated endocytosis. Predicted to act upstream of or within endocytosis. Predicted to be located in membrane. Predicted to be part of receptor complex. Predicted to be active in apical plasma membrane. Human ortholog(s) of this gene implicated in Donnai-Barrow syndrome and autoimmune thyroiditis. Orthologous to human LRP2 (LDL receptor related protein 2). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	12	NC_007123.7 (16132614..16229404)
105	previous assembly	GRCz10 (GCF_000002035.5)	12	NC_007123.6 (16086528..16180594)

Chromosome 12 - NC_007123.7 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info
enables hormone binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in animal organ development	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within endocytosis	IEA Inferred from Electronic Annotation more info
involved_in receptor-mediated endocytosis	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in apical plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
part_of receptor complex	IBA Inferred from Biological aspect of Ancestor more info