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susd5 sushi domain containing 5 [ Danio rerio (zebrafish) ]

Gene ID: 101886789, updated on 12-Sep-2024

Summary

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Official Symbol
susd5provided by ZNC
Official Full Name
sushi domain containing 5provided by ZNC
Primary source
ZFIN:ZDB-GENE-120215-196
See related
Ensembl:ENSDARG00000088277 AllianceGenome:ZFIN:ZDB-GENE-120215-196
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:ch211-207c15.6
Summary
Predicted to enable hyaluronic acid binding activity. Predicted to be involved in Notch signaling pathway. Predicted to act upstream of or within cell adhesion. Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human SUSD5 (sushi domain containing 5). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See susd5 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (42624854..42651657, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (43060059..43082209, complement)

Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene FKBP prolyl isomerase 9 Neighboring gene cartilage associated protein Neighboring gene uncharacterized LOC103909275 Neighboring gene F-box and leucine-rich repeat protein 2 Neighboring gene cytoplasmic linker associated protein 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Crtap and p3h1 knock out zebrafish support defective collagen chaperoning as the cause of their osteogenesis imperfecta phenotype. Tonelli F, et al. Matrix Biol, 2020 Aug. PMID 32173581
  2. Hypoxia-inducible factor 3 is an oxygen-dependent transcription activator and regulates a distinct transcriptional response to hypoxia. Zhang P, et al. Cell Rep, 2014 Mar 27. PMID 24613356
  3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables hyaluronic acid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in Notch signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within cell adhesion IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
sushi domain-containing protein 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007130.7 Reference GRCz11 Primary Assembly

    Range
    42624854..42651657 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005159753.5 → XP_005159810.1  sushi domain-containing protein 5

    See identical proteins and their annotated locations for XP_005159810.1

    UniProtKB/TrEMBL
    A0A8M3ASV6, E7EYM4
    Conserved Domains (3) summary
    cd12094
    Location:577 → 613
    TM_ErbB2; Transmembrane domain of ErbB2, a Protein Tyrosine Kinase
    pfam00084
    Location:129 → 186
    Sushi; Sushi repeat (SCR repeat)
    cl02612
    Location:28 → 122
    Link_Domain; The link domain is a hyaluronan (HA)-binding domain. It functions to mediate adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It is found in the CD44 receptor and in human TSG-6. TSG-6 is the protein product of the tumor ...

  2. XM_009294430.4 → XP_009292705.1  sushi domain-containing protein 5

    See identical proteins and their annotated locations for XP_009292705.1

    UniProtKB/TrEMBL
    A0A8M3ASV6, E7EYM4
    Related
    ENSDARP00000109477.2, ENSDART00000123360.3
    Conserved Domains (3) summary
    cd12094
    Location:577 → 613
    TM_ErbB2; Transmembrane domain of ErbB2, a Protein Tyrosine Kinase
    pfam00084
    Location:129 → 186
    Sushi; Sushi repeat (SCR repeat)
    cl02612
    Location:28 → 122
    Link_Domain; The link domain is a hyaluronan (HA)-binding domain. It functions to mediate adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It is found in the CD44 receptor and in human TSG-6. TSG-6 is the protein product of the tumor ...
Nucleotide Protein
Heading Accession and Version

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