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mir7146 microRNA mir-7146 [ Danio rerio (zebrafish) ]

Gene ID: 102466226, updated on 12-Sep-2024

Summary

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Gene symbol
mir7146
Gene description
microRNA mir-7146
See related
Ensembl:ENSDARG00000100135 miRBase:MI0023605
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
dre-mir-7146
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

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See mir7146 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (5074924..5075054)
105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (5032011..5032141)

Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene AT-rich interactive domain 1B Neighboring gene si:dkey-60a16.1 Neighboring gene cyclin K Neighboring gene cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 1 Neighboring gene cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transcriptome-wide analysis of small RNA expression in early zebrafish development. Wei C, et al. RNA, 2012 May. PMID 22408181, Free PMC Article
  2. miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381832, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Other Names

  • microRNA 7146

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_105067.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    BX649499
    Related
    ENSDART00000167662.2

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007131.7 Reference GRCz11 Primary Assembly

    Range
    5074924..5075054
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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