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nipbla NIPBL cohesin loading factor a [ Lepisosteus oculatus (spotted gar) ]

Gene ID: 102683364, updated on 10-Mar-2024

Summary

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Gene symbol
nipbla
Gene description
NIPBL cohesin loading factor a
See related
Ensembl:ENSLOCG00000012704
Gene type
protein coding
RefSeq status
MODEL
Organism
Lepisosteus oculatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae; Lepisosteus
Also known as
nipbl
Orthologs
human zebrafish all
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Genomic context

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See nipbla in Genome Data Viewer
Location:
chromosome: LG2
Exon count:
50
Annotation release Status Assembly LG Location
101 current LepOcu1 (GCF_000242695.1) LG2 NC_023180.1 (54053540..54146760, complement)

Linkage Group LG2 - NC_023180.1Genomic Context describing neighboring genes Neighboring gene neuropeptide Y receptor type 6-like Neighboring gene nucleoporin 155 Neighboring gene ciliogenesis and planar polarity effector 1 Neighboring gene solute carrier family 1 member 3a Neighboring gene RAN binding protein 3 like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_023180.1 Chromosome LG2 Reference LepOcu1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables chromatin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in brain development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in digestive tract development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in embryonic viscerocranium morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment of mitotic sister chromatid cohesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment of protein localization to chromatin IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in heart morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitotic cohesin loading IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in replication-born double-strand break repair via sister chromatid exchange IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of Scc2-Scc4 cohesin loading complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
nipped-B-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Lepisosteus oculatus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference LepOcu1 Primary Assembly

Genomic

  1. NC_023180.1 Reference LepOcu1 Primary Assembly

    Range
    54053540..54146760 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015340372.1 → XP_015195858.1  nipped-B-like protein isoform X1

    UniProtKB/TrEMBL
    W5N4U2
    Conserved Domains (5) summary
    pfam12533
    Location:156 → 253
    Neuro_bHLH; Neuronal helix-loop-helix transcription factor
    pfam12765
    Location:1784 → 1825
    Cohesin_HEAT; HEAT repeat associated with sister chromatid cohesion
    pfam12830
    Location:2270 → 2444
    Nipped-B_C; Sister chromatid cohesion C-terminus
    pfam15440
    Location:801 → 1157
    THRAP3_BCLAF1; THRAP3/BCLAF1 family
    sd00044
    Location:1801 → 1829
    HEAT; HEAT repeat [structural motif]

  2. XM_015340371.1 → XP_015195857.1  nipped-B-like protein isoform X1

    UniProtKB/TrEMBL
    W5N4U2
    Conserved Domains (5) summary
    pfam12533
    Location:156 → 253
    Neuro_bHLH; Neuronal helix-loop-helix transcription factor
    pfam12765
    Location:1784 → 1825
    Cohesin_HEAT; HEAT repeat associated with sister chromatid cohesion
    pfam12830
    Location:2270 → 2444
    Nipped-B_C; Sister chromatid cohesion C-terminus
    pfam15440
    Location:801 → 1157
    THRAP3_BCLAF1; THRAP3/BCLAF1 family
    sd00044
    Location:1801 → 1829
    HEAT; HEAT repeat [structural motif]

  3. XM_015340370.1 → XP_015195856.1  nipped-B-like protein isoform X1

    UniProtKB/TrEMBL
    W5N4U2
    Conserved Domains (5) summary
    pfam12533
    Location:156 → 253
    Neuro_bHLH; Neuronal helix-loop-helix transcription factor
    pfam12765
    Location:1784 → 1825
    Cohesin_HEAT; HEAT repeat associated with sister chromatid cohesion
    pfam12830
    Location:2270 → 2444
    Nipped-B_C; Sister chromatid cohesion C-terminus
    pfam15440
    Location:801 → 1157
    THRAP3_BCLAF1; THRAP3/BCLAF1 family
    sd00044
    Location:1801 → 1829
    HEAT; HEAT repeat [structural motif]

  4. XM_015340373.1 → XP_015195859.1  nipped-B-like protein isoform X2

    UniProtKB/TrEMBL
    W5N4U2
    Conserved Domains (5) summary
    pfam12533
    Location:146 → 243
    Neuro_bHLH; Neuronal helix-loop-helix transcription factor
    pfam12765
    Location:1774 → 1815
    Cohesin_HEAT; HEAT repeat associated with sister chromatid cohesion
    pfam12830
    Location:2260 → 2434
    Nipped-B_C; Sister chromatid cohesion C-terminus
    pfam15440
    Location:791 → 1147
    THRAP3_BCLAF1; THRAP3/BCLAF1 family
    sd00044
    Location:1791 → 1819
    HEAT; HEAT repeat [structural motif]

  5. XM_015340369.1 → XP_015195855.1  nipped-B-like protein isoform X1

    UniProtKB/TrEMBL
    W5N4U2
    Conserved Domains (5) summary
    pfam12533
    Location:156 → 253
    Neuro_bHLH; Neuronal helix-loop-helix transcription factor
    pfam12765
    Location:1784 → 1825
    Cohesin_HEAT; HEAT repeat associated with sister chromatid cohesion
    pfam12830
    Location:2270 → 2444
    Nipped-B_C; Sister chromatid cohesion C-terminus
    pfam15440
    Location:801 → 1157
    THRAP3_BCLAF1; THRAP3/BCLAF1 family
    sd00044
    Location:1801 → 1829
    HEAT; HEAT repeat [structural motif]

  6. XM_015340374.1 → XP_015195860.1  nipped-B-like protein isoform X3

    UniProtKB/TrEMBL
    W5N4U2
    Related
    ENSLOCP00000015651.1, ENSLOCT00000015680.1
    Conserved Domains (5) summary
    pfam09786
    Location:129 → 317
    CytochromB561_N; Cytochrome B561, N terminal
    pfam12765
    Location:1742 → 1783
    Cohesin_HEAT; HEAT repeat associated with sister chromatid cohesion
    pfam12830
    Location:2228 → 2402
    Nipped-B_C; Sister chromatid cohesion C-terminus
    pfam15440
    Location:759 → 1115
    THRAP3_BCLAF1; THRAP3/BCLAF1 family
    sd00044
    Location:1759 → 1787
    HEAT; HEAT repeat [structural motif]

  7. XM_015340375.1 → XP_015195861.1  nipped-B-like protein isoform X4

    Conserved Domains (5) summary
    pfam08648
    Location:602 → 752
    DUF1777; Protein of unknown function (DUF1777)
    pfam09786
    Location:141 → 359
    CytochromB561_N; Cytochrome B561, N terminal
    pfam12765
    Location:1292 → 1333
    Cohesin_HEAT; HEAT repeat associated with sister chromatid cohesion
    pfam12830
    Location:1778 → 1952
    Nipped-B_C; Sister chromatid cohesion C-terminus
    sd00044
    Location:1309 → 1337
    HEAT; HEAT repeat [structural motif]
Nucleotide Protein
Heading Accession and Version

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