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fbxo48 F-box protein 48 [ Danio rerio (zebrafish) ]

Gene ID: 103908695, updated on 18-Sep-2024

Summary

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Official Symbol
fbxo48provided by ZNC
Official Full Name
F-box protein 48provided by ZNC
Primary source
ZFIN:ZDB-GENE-121214-308
See related
Ensembl:ENSDARG00000086184 AllianceGenome:ZFIN:ZDB-GENE-121214-308
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:dkey-202b17.4
Summary
Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See fbxo48 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (51608194..51615476, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (50964395..50971677, complement)

Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene protein phosphatase 3 (formerly 2B), regulatory s1ubunit B, alpha isoform, b Neighboring gene cannabinoid receptor interacting protein 1a Neighboring gene aprataxin and PNKP like factor Neighboring gene prokineticin receptor 1a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of SCF ubiquitin ligase complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
F-box only protein 48

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001328021.1 → NP_001314950.1  F-box only protein 48 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (a). Variants 1, 2 and 3 all encode isoform a.
    Source sequence(s)
    CU929104, EH464114, EH546124, EH556733
    UniProtKB/TrEMBL
    A0A8M1P8P2, R4GEA9, X1WH10
    Related
    ENSDARP00000127022.1, ENSDART00000152595.3
    Conserved Domains (1) summary
    pfam12937
    Location:35 → 81
    F-box-like; F-box-like

  2. NM_001328023.1 → NP_001314952.1  F-box only protein 48 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 all encode isoform a.
    Source sequence(s)
    CU929104, EH445891, EH464114, EH546124
    UniProtKB/TrEMBL
    A0A8M1P8P2, R4GEA9, X1WH10
    Related
    ENSDARP00000127027.1, ENSDART00000152237.3
    Conserved Domains (1) summary
    pfam12937
    Location:35 → 81
    F-box-like; F-box-like

  3. NM_001328024.1 → NP_001314953.1  F-box only protein 48 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 all encode isoform a.
    Source sequence(s)
    CU929104, EH464114, EH546124
    UniProtKB/TrEMBL
    A0A8M1P8P2, R4GEA9, X1WH10
    Related
    ENSDARP00000126822.1, ENSDART00000152185.3
    Conserved Domains (1) summary
    pfam12937
    Location:35 → 81
    F-box-like; F-box-like

  4. NM_001328025.1 → NP_001314954.1  F-box only protein 48 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) contains an additional internal exon that results in a frameshift in the 3' coding region, compared to variant 1. The encoded isoform (b) has a distinct C-terminus and is shorter than isoform a.
    Source sequence(s)
    CU929104, EH464114, EH501007, EH546124
    UniProtKB/TrEMBL
    A0A8M1P9E5, F1QC12
    Related
    ENSDARP00000106099.2, ENSDART00000129052.3
    Conserved Domains (1) summary
    pfam12937
    Location:35 → 81
    F-box-like; F-box-like

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007112.7 Reference GRCz11 Primary Assembly

    Range
    51608194..51615476 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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