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syt8 synaptotagmin VIII [ Danio rerio (zebrafish) ]

Gene ID: 103909874, updated on 28-Oct-2024

Summary

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Official Symbol
syt8provided by ZNC
Official Full Name
synaptotagmin VIIIprovided by ZNC
Primary source
ZFIN:ZDB-GENE-060303-4
See related
AllianceGenome:ZFIN:ZDB-GENE-060303-4
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to be located in membrane. Orthologous to human SYT8 (synaptotagmin 8). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
all
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Genomic context

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See syt8 in Genome Data Viewer
Location:
chromosome: 25
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (31175696..31195580)
105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (31109186..31124211)

Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene ras association domain-containing protein 8 Neighboring gene cytosolic 5'-nucleotidase 1A Neighboring gene uncharacterized LOC101884923 Neighboring gene troponin I type 2a (skeletal, fast), tandem duplicate 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Cytoplasmic pool of U1 spliceosome protein SNRNP70 shapes the axonal transcriptome and regulates motor connectivity. Nikolaou N, et al. Curr Biol, 2022 Dec 5. PMID 36384140
  2. Expression and distribution of synaptotagmin family members in the zebrafish retina. Henry D, et al. J Comp Neurol, 2022 Mar. PMID 34468021, Free PMC Article
  3. Evolutionary genomics of plant genes encoding N-terminal-TM-C2 domain proteins and the similar FAM62 genes and synaptotagmin genes of metazoans. Craxton M. BMC Genomics, 2007 Jul 31. PMID 17672888, Free PMC Article
  4. Functional analysis reveals no transcriptional role for the glucocorticoid receptor β-isoform in zebrafish. Chatzopoulou A, et al. Mol Cell Endocrinol, 2017 May 15. PMID 28242321
  5. A manual collection of Syt, Esyt, Rph3a, Rph3al, Doc2, and Dblc2 genes from 46 metazoan genomes--an open access resource for neuroscience and evolutionary biology. Craxton M. BMC Genomics, 2010 Jan 15. PMID 20078875, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
synaptotagmin VIII
Names
synaptotagmin-1-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001365289.1 → NP_001352218.1  synaptotagmin VIII isoform 1

    Status: VALIDATED

    Source sequence(s)
    FQ976913
    UniProtKB/TrEMBL
    A0A8M9PND4
    Conserved Domains (2) summary
    cd08385
    Location:106 → 229
    C2A_Synaptotagmin-1-5-6-9-10; C2A domain first repeat present in Synaptotagmins 1, 5, 6, 9, and 10
    cd08402
    Location:238 → 372
    C2B_Synaptotagmin-1; C2 domain second repeat present in Synaptotagmin 1

  2. NM_001365290.1 → NP_001352219.1  synaptotagmin VIII isoform 2

    Status: VALIDATED

    Source sequence(s)
    FQ976913
    UniProtKB/TrEMBL
    A0A8M9PVL9
    Conserved Domains (2) summary
    cd08402
    Location:206 → 340
    C2B_Synaptotagmin-1; C2 domain second repeat present in Synaptotagmin 1
    cl14603
    Location:87 → 197
    C2; C2 domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007136.7 Reference GRCz11 Primary Assembly

    Range
    31175696..31195580
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068217304.1 → XP_068073405.1  synaptotagmin VIII isoform X1

  2. XM_021470717.2 → XP_021326392.1  synaptotagmin VIII isoform X2

    UniProtKB/TrEMBL
    A0A8M9P6W9
    Conserved Domains (2) summary
    cd08385
    Location:73 → 196
    C2A_Synaptotagmin-1-5-6-9-10; C2A domain first repeat present in Synaptotagmins 1, 5, 6, 9, and 10
    cd08402
    Location:205 → 339
    C2B_Synaptotagmin-1; C2 domain second repeat present in Synaptotagmin 1
Nucleotide Protein Strain
Heading Accession and Version

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