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mctp1a multiple C2 domains, transmembrane 1a [ Danio rerio (zebrafish) ]

Gene ID: 103911113, updated on 28-Oct-2024

Summary

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Official Symbol
mctp1aprovided by ZNC
Official Full Name
multiple C2 domains, transmembrane 1aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-110125-3
See related
Ensembl:ENSDARG00000076404 AllianceGenome:ZFIN:ZDB-GENE-110125-3
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
mctp1
Summary
Predicted to be located in membrane. Is expressed in several structures, including central nervous system; embryonic structure; notochord; optic cup; and pronephric duct. Orthologous to human MCTP1 (multiple C2 and transmembrane domain containing 1). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
human mouse all
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Genomic context

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See mctp1a in Genome Data Viewer
Location:
chromosome: 5
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (50445947..50701806, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (49795532..50055168, complement)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene si:ch73-280o22.2 Neighboring gene SMC5-SMC6 complex localization factor 1 Neighboring gene uncharacterized LOC137495631 Neighboring gene uncharacterized LOC110439828 Neighboring gene zgc:194908 Neighboring gene family with sequence similarity 81 member B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Temporal and spatial expression of zebrafish mctp genes and evaluation of frameshift alleles of mctp2b. Espino-Saldaña AE, et al. Gene, 2020 May 15. PMID 32001375
  2. Shutdown corner, a large deletion mutant isolated from a haploid mutagenesis screen in zebrafish. Casey MA, et al. G3 (Bethesda), 2022 Mar 4. PMID 35079792, Free PMC Article
  3. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
multiple C2 and transmembrane domain-containing protein 1
Names
multiple C2 domain and transmembrane region protein 1a
multiple C2 domains, transmembrane 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    50445947..50701806 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068221519.1 → XP_068077620.1  multiple C2 and transmembrane domain-containing protein 1 isoform X3

    Related
    ENSDARP00000097628.4, ENSDART00000113985.4

  2. XM_068221518.1 → XP_068077619.1  multiple C2 and transmembrane domain-containing protein 1 isoform X2

    Related
    ENSDARP00000155267.1, ENSDART00000183353.1

  3. XM_009301796.4 → XP_009300071.1  multiple C2 and transmembrane domain-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8M3B9W7
    Conserved Domains (4) summary
    cd04042
    Location:36 → 157
    C2A_MCTP_PRT; C2 domain first repeat found in Multiple C2 domain and Transmembrane region Proteins (MCTP)
    cd08376
    Location:197 → 312
    C2B_MCTP_PRT; C2 domain second repeat found in Multiple C2 domain and Transmembrane region Proteins (MCTP)
    cd08377
    Location:352 → 470
    C2C_MCTP_PRT; C2 domain third repeat found in Multiple C2 domain and Transmembrane region Proteins (MCTP)
    pfam08372
    Location:648 → 705
    PRT_C; Plant phosphoribosyltransferase C-terminal
Nucleotide Protein Strain
Heading Accession and Version

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