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SEMA4D semaphorin 4D [ Homo sapiens (human) ]

Gene ID: 10507, updated on 29-Oct-2024

Summary

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Official Symbol
SEMA4Dprovided by HGNC
Official Full Name
semaphorin 4Dprovided by HGNC
Primary source
HGNC:HGNC:10732
See related
Ensembl:ENSG00000187764 MIM:601866; AllianceGenome:HGNC:10732
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
A8; GR3; BB18; CD100; COLL4; SEMAJ; coll-4; C9orf164; M-sema-G
Summary
Enables identical protein binding activity; semaphorin receptor binding activity; and transmembrane signaling receptor activity. Involved in several processes, including ossification involved in bone maturation; positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction; and regulation of neuron projection development. Located in plasma membrane. [provided by Alliance of Genome Resources, Oct 2024]
Expression
Broad expression in lymph node (RPKM 12.0), appendix (RPKM 8.6) and 22 other tissues See more
Orthologs
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Genomic context

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See SEMA4D in Genome Data Viewer
Location:
9q22.2
Exon count:
34
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (89360787..89498113, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (101524564..101662071, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (91975702..92113028, complement)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105376136 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:91896966-91897484 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20005 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20006 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28527 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28528 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28529 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20007 Neighboring gene microRNA 3153 Neighboring gene SECIS binding protein 2 Neighboring gene CDC28 protein kinase regulatory subunit 2 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:91978812-91979312 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:91979313-91979813 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28530 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20008 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28531 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_108523 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_108535 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:92020317-92021138 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:92021139-92021959 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28535 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:92026366-92026868 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:92026869-92027370 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr9:92027622-92028122 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr9:92028123-92028623 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28536 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28537 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:92040313-92041172 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28538 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28539 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28540 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28542 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28541 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28543 Neighboring gene H3K27ac hESC enhancer GRCh37_chr9:92046837-92047618 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:92049183-92049964 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:92049965-92050746 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:92050747-92051528 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:92051529-92052310 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:92054729-92055306 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:92057617-92058192 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_108605 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:92061728-92062338 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:92064045-92064893 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20009 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28545 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:92080560-92081256 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:92081257-92081952 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:92082322-92083285 Neighboring gene proliferation-associated 2G4 pseudogene 6 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28546 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:92086209-92086710 Neighboring gene ubiquitin-conjugating enzyme E2 variant 1-like Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:92095373-92095872 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:92096528-92097028 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20010 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20011 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28547 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20012 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20013 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20014 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28548 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28549 Neighboring gene uncharacterized LOC105376137 Neighboring gene Neanderthal introgressed variant-containing enhancers experimental_108656 and experimental_108657 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_108660 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_108664 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_108676 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_108670 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28550 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28551 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28552 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20015 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28553 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_108683 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:92167973-92168574 Neighboring gene uncharacterized LOC124902207 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28554

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Semaphorin 4D expression is associated with a poor clinical outcome in cervical cancer patients. Liu H, et al. Microvasc Res, 2014 May. PMID 24603190
  2. Semaphorin 4D promotes the proliferation and metastasis of bladder cancer by activating the PI3K/AKT pathway. Lu JJ, et al. Tumori, 2019 Jun. PMID 30674231, Free PMC Article
  3. Circulating Semaphorin 4D as a Marker for Predicting Radiographic Progression in Patients with Rheumatoid Arthritis. Ha YJ, et al. Dis Markers, 2018. PMID 30538782, Free PMC Article
  4. Semaphorin 4D correlates with increased bone resorption, hypercalcemia, and disease stage in newly diagnosed patients with multiple myeloma. Terpos E, et al. Blood Cancer J, 2018 May 11. PMID 29748532, Free PMC Article
  5. VEGF and SEMA4D have synergistic effects on the promotion of angiogenesis in epithelial ovarian cancer. Chen Y, et al. Cell Mol Biol Lett, 2018. PMID 29308068, Free PMC Article

See all (135) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. PLXNB1/SEMA4D signals mediate interactions between malignant epithelial and immune cells to promote colorectal cancer liver metastasis.
    Title: PLXNB1/SEMA4D signals mediate interactions between malignant epithelial and immune cells to promote colorectal cancer liver metastasis.
  2. Comparative evaluation of semaphorin-4D, peptidylarginine deiminase-2, and matrix metalloproteinase-8 levels of gingival crevicular fluid in periodontally healthy and Stage III periodontitis smoker and non-smoker patients before and after non-surgical periodontal therapy.
    Title: Comparative evaluation of semaphorin-4D, peptidylarginine deiminase-2, and matrix metalloproteinase-8 levels of gingival crevicular fluid in periodontally healthy and Stage III periodontitis smoker and non-smoker patients before and after non-surgical periodontal therapy.
  3. Sema4D as a biomarker for Predicting rheumatoid arthritis disease activity.
    Title: Sema4D as a biomarker for Predicting rheumatoid arthritis disease activity.
  4. Protection of Barrier Function in Cultured Human Corneal Epithelial Cells by Semaphorin 4D.
    Title: Protection of Barrier Function in Cultured Human Corneal Epithelial Cells by Semaphorin 4D.
  5. The Potential Immunomodulatory Roles of Semaphorin 4D in Human Periapical Lesions.
    Title: The Potential Immunomodulatory Roles of Semaphorin 4D in Human Periapical Lesions.
  6. Soluble Sema4D Level Is Positively Correlated with Sema4D Expression in PBMCs and Peripheral Blast Number in Acute Leukemia.
    Title: Soluble Sema4D Level Is Positively Correlated with Sema4D Expression in PBMCs and Peripheral Blast Number in Acute Leukemia.
  7. Sema4D correlates with tumour immune infiltration and is a prognostic biomarker in bladder cancer, renal clear cell carcinoma, melanoma and thymoma.
    Title: Sema4D correlates with tumour immune infiltration and is a prognostic biomarker in bladder cancer, renal clear cell carcinoma, melanoma and thymoma.
  8. Sema4D/Plexin-B1 promotes the progression of osteosarcoma cells by activating Pyk2-PI3K-AKT pathway.
    Title: Sema4D/Plexin-B1 promotes the progression of osteosarcoma cells by activating Pyk2-PI3K-AKT pathway.
  9. CD100 modulates cytotoxicity of CD8(+) T cells in patients with acute myocardial infarction.
    Title: CD100 modulates cytotoxicity of CD8(+) T cells in patients with acute myocardial infarction.
  10. Assessment of the relationship between semaphorin4D level and recurrence after catheter ablation in paroxysmal atrial fibrillation.
    Title: Assessment of the relationship between semaphorin4D level and recurrence after catheter ablation in paroxysmal atrial fibrillation.
Submit: New GeneRIF Correction See all GeneRIFs (93)

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

HIV-1 interactions

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Replication interactions

Interaction Pubs
HIV-1 infection (VSV-G pseudotyped) of CEMT4 T cells downregulates plasma membrane expression of SEMA4D PubMed

Protein interactions

Protein Gene Interaction Pubs
Envelope surface glycoprotein gp120 env HIV-1 gp120 upregulates the expression of semaphoring-4D (SEMA4D) in human B cells PubMed
Nef nef Both HIV-1 Nef and Vpu downregulate the cell surface expression of CD100 PubMed
Tat tat Microarray analysis indicates HIV-1 Tat upregulates the expression of many proteins, including Semaphorin (CD100), in immature dendritic cells, an effect that likely facilitates the expansion of HIV-1 infection PubMed
Vpu vpu Both HIV-1 Nef and Vpu downregulate the cell surface expression of CD100 PubMed

Go to the HIV-1, Human Interaction Database

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • FLJ33485, FLJ34282, FLJ39737, FLJ46484, MGC169138, MGC169141

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables chemorepellent activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables identical protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables neuropilin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables receptor ligand activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables semaphorin receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables semaphorin receptor binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables semaphorin receptor binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables signaling receptor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables signaling receptor binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables transmembrane signaling receptor activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in axon guidance IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in bone trabecula morphogenesis ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in cell adhesion TAS
Traceable Author Statement
more info
 PubMed 
involved_in immune response TAS
Traceable Author Statement
more info
 PubMed 
involved_in leukocyte aggregation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative chemotaxis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of apoptotic process TAS
Traceable Author Statement
more info
 PubMed 
involved_in negative regulation of cell adhesion IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in negative regulation of osteoblast differentiation ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in negative regulation of peptidyl-tyrosine phosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in neural crest cell migration IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ossification involved in bone maturation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of GTPase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of Rho protein signal transduction ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in positive regulation of cell migration IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of cell migration IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in positive regulation of cell migration ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in positive regulation of collateral sprouting IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of inhibitory synapse assembly ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in positive regulation of peptidyl-tyrosine phosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of protein phosphorylation IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of cell projection organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of cell shape IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of dendrite morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in semaphorin-plexin signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in semaphorin-plexin signaling pathway IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in semaphorin-plexin signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in semaphorin-plexin signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in GABA-ergic synapse IEA
Inferred from Electronic Annotation
more info
  
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in extracellular space ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane TAS
Traceable Author Statement
more info
  
located_in postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
  
part_of semaphorin receptor complex ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
semaphorin-4D
Names
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, 4D

NCBI Reference Sequences (RefSeq)

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NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001142287.2 → NP_001135759.1  semaphorin-4D isoform 2 precursor

    See identical proteins and their annotated locations for NP_001135759.1

    Status: VALIDATED

    Source sequence(s)
    AL590233, AL929575
    Consensus CDS
    CCDS47991.1
    Related
    ENSP00000391733.1, ENST00000420987.5
    Conserved Domains (4) summary
    cd11259
    Location:31 → 501
    Sema_4D; The Sema domain, a protein interacting module, of semaphorin 4D (Sema4D, also known as CD100)
    pfam01437
    Location:503 → 554
    PSI; Plexin repeat
    cd00096
    Location:604 → 612
    Ig; Ig strand A [structural motif]
    cl11960
    Location:603 → 690
    Ig; Immunoglobulin domain

  2. NM_001371194.2 → NP_001358123.1  semaphorin-4D isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AL590233, AL929575
    Consensus CDS
    CCDS6685.1
    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854
    UniProtKB/TrEMBL
    Q4LE41
    Related
    ENSP00000388768.2, ENST00000422704.7
    Conserved Domains (3) summary
    cd05873
    Location:559 → 645
    Ig_Sema4D_like; Immunoglobulin (Ig)-like domain of the class IV semaphorin Sema4D
    cd11259
    Location:31 → 501
    Sema_4D; The Sema domain, a protein interacting module, of semaphorin 4D (Sema4D, also known as CD100)
    smart00423
    Location:503 → 554
    PSI; domain found in Plexins, Semaphorins and Integrins

  3. NM_001371195.1 → NP_001358124.1  semaphorin-4D isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AL590233, AL929575
    Consensus CDS
    CCDS6685.1
    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854
    UniProtKB/TrEMBL
    Q4LE41
    Conserved Domains (3) summary
    cd05873
    Location:559 → 645
    Ig_Sema4D_like; Immunoglobulin (Ig)-like domain of the class IV semaphorin Sema4D
    cd11259
    Location:31 → 501
    Sema_4D; The Sema domain, a protein interacting module, of semaphorin 4D (Sema4D, also known as CD100)
    smart00423
    Location:503 → 554
    PSI; domain found in Plexins, Semaphorins and Integrins

  4. NM_001371196.1 → NP_001358125.1  semaphorin-4D isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AL590233, AL929575
    Consensus CDS
    CCDS6685.1
    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854
    UniProtKB/TrEMBL
    Q4LE41
    Conserved Domains (3) summary
    cd05873
    Location:559 → 645
    Ig_Sema4D_like; Immunoglobulin (Ig)-like domain of the class IV semaphorin Sema4D
    cd11259
    Location:31 → 501
    Sema_4D; The Sema domain, a protein interacting module, of semaphorin 4D (Sema4D, also known as CD100)
    smart00423
    Location:503 → 554
    PSI; domain found in Plexins, Semaphorins and Integrins

  5. NM_001371197.1 → NP_001358126.1  semaphorin-4D isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AL590233, AL929575
    Consensus CDS
    CCDS6685.1
    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854
    UniProtKB/TrEMBL
    Q4LE41
    Conserved Domains (3) summary
    cd05873
    Location:559 → 645
    Ig_Sema4D_like; Immunoglobulin (Ig)-like domain of the class IV semaphorin Sema4D
    cd11259
    Location:31 → 501
    Sema_4D; The Sema domain, a protein interacting module, of semaphorin 4D (Sema4D, also known as CD100)
    smart00423
    Location:503 → 554
    PSI; domain found in Plexins, Semaphorins and Integrins

  6. NM_001371198.1 → NP_001358127.1  semaphorin-4D isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AL590233, AL929575
    Consensus CDS
    CCDS47991.1
    Conserved Domains (4) summary
    cd11259
    Location:31 → 501
    Sema_4D; The Sema domain, a protein interacting module, of semaphorin 4D (Sema4D, also known as CD100)
    pfam01437
    Location:503 → 554
    PSI; Plexin repeat
    cd00096
    Location:604 → 612
    Ig; Ig strand A [structural motif]
    cl11960
    Location:603 → 690
    Ig; Immunoglobulin domain

  7. NM_001371199.1 → NP_001358128.1  semaphorin-4D isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AL590233, AL929575
    Consensus CDS
    CCDS47991.1
    Conserved Domains (4) summary
    cd11259
    Location:31 → 501
    Sema_4D; The Sema domain, a protein interacting module, of semaphorin 4D (Sema4D, also known as CD100)
    pfam01437
    Location:503 → 554
    PSI; Plexin repeat
    cd00096
    Location:604 → 612
    Ig; Ig strand A [structural motif]
    cl11960
    Location:603 → 690
    Ig; Immunoglobulin domain

  8. NM_001371200.1 → NP_001358129.1  semaphorin-4D isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AL590233, AL929575
    Consensus CDS
    CCDS47991.1
    Conserved Domains (4) summary
    cd11259
    Location:31 → 501
    Sema_4D; The Sema domain, a protein interacting module, of semaphorin 4D (Sema4D, also known as CD100)
    pfam01437
    Location:503 → 554
    PSI; Plexin repeat
    cd00096
    Location:604 → 612
    Ig; Ig strand A [structural motif]
    cl11960
    Location:603 → 690
    Ig; Immunoglobulin domain

  9. NM_001371201.1 → NP_001358130.1  semaphorin-4D isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AL590233, AL929575
    Consensus CDS
    CCDS47991.1
    Conserved Domains (4) summary
    cd11259
    Location:31 → 501
    Sema_4D; The Sema domain, a protein interacting module, of semaphorin 4D (Sema4D, also known as CD100)
    pfam01437
    Location:503 → 554
    PSI; Plexin repeat
    cd00096
    Location:604 → 612
    Ig; Ig strand A [structural motif]
    cl11960
    Location:603 → 690
    Ig; Immunoglobulin domain

  10. NM_001371202.1 → NP_001358131.1  semaphorin-4D isoform 3 precursor

    Status: VALIDATED

    Source sequence(s)
    AL590233, AL929575
    Conserved Domains (2) summary
    cd11259
    Location:31 → 501
    Sema_4D; The Sema domain, a protein interacting module, of semaphorin 4D (Sema4D, also known as CD100)
    smart00423
    Location:503 → 554
    PSI; domain found in Plexins, Semaphorins and Integrins

  11. NM_006378.4 → NP_006369.3  semaphorin-4D isoform 1 precursor

    See identical proteins and their annotated locations for NP_006369.3

    Status: VALIDATED

    Source sequence(s)
    AL590233, AL929575
    Consensus CDS
    CCDS6685.1
    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854
    UniProtKB/TrEMBL
    Q4LE41
    Related
    ENSP00000405102.2, ENST00000438547.6
    Conserved Domains (3) summary
    cd05873
    Location:559 → 645
    Ig_Sema4D_like; Immunoglobulin (Ig)-like domain of the class IV semaphorin Sema4D
    cd11259
    Location:31 → 501
    Sema_4D; The Sema domain, a protein interacting module, of semaphorin 4D (Sema4D, also known as CD100)
    smart00423
    Location:503 → 554
    PSI; domain found in Plexins, Semaphorins and Integrins

RNA

  1. NR_163884.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL590233, AL929575

  2. NR_163885.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL590233, AL929575

  3. NR_163886.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL590233, AL929575

  4. NR_163887.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL590233, AL929575

  5. NR_163888.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL590233, AL929575

  6. NR_163889.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL590233, AL929575

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    89360787..89498113 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047422627.1 → XP_047278583.1  semaphorin-4D isoform X3

    Related
    ENSP00000411981.2, ENST00000455551.6

  2. XM_047422624.1 → XP_047278580.1  semaphorin-4D isoform X3

  3. XM_047422620.1 → XP_047278576.1  semaphorin-4D isoform X2

  4. XM_047422623.1 → XP_047278579.1  semaphorin-4D isoform X2

  5. XM_047422628.1 → XP_047278584.1  semaphorin-4D isoform X3

  6. XM_047422622.1 → XP_047278578.1  semaphorin-4D isoform X2

  7. XM_047422626.1 → XP_047278582.1  semaphorin-4D isoform X3

    Related
    ENSP00000344923.4, ENST00000339861.8

  8. XM_047422621.1 → XP_047278577.1  semaphorin-4D isoform X2

  9. XM_047422625.1 → XP_047278581.1  semaphorin-4D isoform X3

  10. XM_047422629.1 → XP_047278585.1  semaphorin-4D isoform X4

    UniProtKB/TrEMBL
    E9PFD9
    Related
    ENSP00000446394.1, ENST00000537934.5

  11. XM_047422607.1 → XP_047278563.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  12. XM_011518125.2 → XP_011516427.1  semaphorin-4D isoform X1

    See identical proteins and their annotated locations for XP_011516427.1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854
    UniProtKB/TrEMBL
    Q4LE41
    Related
    ENSP00000348822.2, ENST00000356444.6
    Conserved Domains (3) summary
    cd05873
    Location:559 → 645
    Ig_Sema4D_like; Immunoglobulin (Ig)-like domain of the class IV semaphorin Sema4D
    cd11259
    Location:31 → 501
    Sema_4D; The Sema domain, a protein interacting module, of semaphorin 4D (Sema4D, also known as CD100)
    smart00423
    Location:503 → 554
    PSI; domain found in Plexins, Semaphorins and Integrins

  13. XM_011518133.3 → XP_011516435.1  semaphorin-4D isoform X1

    See identical proteins and their annotated locations for XP_011516435.1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854
    UniProtKB/TrEMBL
    Q4LE41
    Conserved Domains (3) summary
    cd05873
    Location:559 → 645
    Ig_Sema4D_like; Immunoglobulin (Ig)-like domain of the class IV semaphorin Sema4D
    cd11259
    Location:31 → 501
    Sema_4D; The Sema domain, a protein interacting module, of semaphorin 4D (Sema4D, also known as CD100)
    smart00423
    Location:503 → 554
    PSI; domain found in Plexins, Semaphorins and Integrins

  14. XM_011518128.3 → XP_011516430.1  semaphorin-4D isoform X1

    See identical proteins and their annotated locations for XP_011516430.1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854
    UniProtKB/TrEMBL
    Q4LE41
    Conserved Domains (3) summary
    cd05873
    Location:559 → 645
    Ig_Sema4D_like; Immunoglobulin (Ig)-like domain of the class IV semaphorin Sema4D
    cd11259
    Location:31 → 501
    Sema_4D; The Sema domain, a protein interacting module, of semaphorin 4D (Sema4D, also known as CD100)
    smart00423
    Location:503 → 554
    PSI; domain found in Plexins, Semaphorins and Integrins

  15. XM_011518127.3 → XP_011516429.1  semaphorin-4D isoform X1

    See identical proteins and their annotated locations for XP_011516429.1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854
    UniProtKB/TrEMBL
    Q4LE41
    Conserved Domains (3) summary
    cd05873
    Location:559 → 645
    Ig_Sema4D_like; Immunoglobulin (Ig)-like domain of the class IV semaphorin Sema4D
    cd11259
    Location:31 → 501
    Sema_4D; The Sema domain, a protein interacting module, of semaphorin 4D (Sema4D, also known as CD100)
    smart00423
    Location:503 → 554
    PSI; domain found in Plexins, Semaphorins and Integrins

  16. XM_047422614.1 → XP_047278570.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  17. XM_047422606.1 → XP_047278562.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  18. XM_011518123.3 → XP_011516425.1  semaphorin-4D isoform X1

    See identical proteins and their annotated locations for XP_011516425.1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854
    UniProtKB/TrEMBL
    Q4LE41
    Conserved Domains (3) summary
    cd05873
    Location:559 → 645
    Ig_Sema4D_like; Immunoglobulin (Ig)-like domain of the class IV semaphorin Sema4D
    cd11259
    Location:31 → 501
    Sema_4D; The Sema domain, a protein interacting module, of semaphorin 4D (Sema4D, also known as CD100)
    smart00423
    Location:503 → 554
    PSI; domain found in Plexins, Semaphorins and Integrins

  19. XM_047422619.1 → XP_047278575.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  20. XM_011518129.2 → XP_011516431.1  semaphorin-4D isoform X1

    See identical proteins and their annotated locations for XP_011516431.1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854
    UniProtKB/TrEMBL
    Q4LE41
    Conserved Domains (3) summary
    cd05873
    Location:559 → 645
    Ig_Sema4D_like; Immunoglobulin (Ig)-like domain of the class IV semaphorin Sema4D
    cd11259
    Location:31 → 501
    Sema_4D; The Sema domain, a protein interacting module, of semaphorin 4D (Sema4D, also known as CD100)
    smart00423
    Location:503 → 554
    PSI; domain found in Plexins, Semaphorins and Integrins

  21. XM_017014198.2 → XP_016869687.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854
    UniProtKB/TrEMBL
    Q4LE41
    Conserved Domains (3) summary
    cd05873
    Location:559 → 645
    Ig_Sema4D_like; Immunoglobulin (Ig)-like domain of the class IV semaphorin Sema4D
    cd11259
    Location:31 → 501
    Sema_4D; The Sema domain, a protein interacting module, of semaphorin 4D (Sema4D, also known as CD100)
    smart00423
    Location:503 → 554
    PSI; domain found in Plexins, Semaphorins and Integrins

  22. XM_047422617.1 → XP_047278573.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  23. XM_047422609.1 → XP_047278565.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  24. XM_017014195.2 → XP_016869684.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854
    UniProtKB/TrEMBL
    Q4LE41
    Conserved Domains (3) summary
    cd05873
    Location:559 → 645
    Ig_Sema4D_like; Immunoglobulin (Ig)-like domain of the class IV semaphorin Sema4D
    cd11259
    Location:31 → 501
    Sema_4D; The Sema domain, a protein interacting module, of semaphorin 4D (Sema4D, also known as CD100)
    smart00423
    Location:503 → 554
    PSI; domain found in Plexins, Semaphorins and Integrins

  25. XM_017014194.2 → XP_016869683.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854
    UniProtKB/TrEMBL
    Q4LE41
    Conserved Domains (3) summary
    cd05873
    Location:559 → 645
    Ig_Sema4D_like; Immunoglobulin (Ig)-like domain of the class IV semaphorin Sema4D
    cd11259
    Location:31 → 501
    Sema_4D; The Sema domain, a protein interacting module, of semaphorin 4D (Sema4D, also known as CD100)
    smart00423
    Location:503 → 554
    PSI; domain found in Plexins, Semaphorins and Integrins

  26. XM_011518124.3 → XP_011516426.1  semaphorin-4D isoform X1

    See identical proteins and their annotated locations for XP_011516426.1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854
    UniProtKB/TrEMBL
    Q4LE41
    Conserved Domains (3) summary
    cd05873
    Location:559 → 645
    Ig_Sema4D_like; Immunoglobulin (Ig)-like domain of the class IV semaphorin Sema4D
    cd11259
    Location:31 → 501
    Sema_4D; The Sema domain, a protein interacting module, of semaphorin 4D (Sema4D, also known as CD100)
    smart00423
    Location:503 → 554
    PSI; domain found in Plexins, Semaphorins and Integrins

  27. XM_017014193.3 → XP_016869682.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854
    UniProtKB/TrEMBL
    Q4LE41
    Conserved Domains (3) summary
    cd05873
    Location:559 → 645
    Ig_Sema4D_like; Immunoglobulin (Ig)-like domain of the class IV semaphorin Sema4D
    cd11259
    Location:31 → 501
    Sema_4D; The Sema domain, a protein interacting module, of semaphorin 4D (Sema4D, also known as CD100)
    smart00423
    Location:503 → 554
    PSI; domain found in Plexins, Semaphorins and Integrins

  28. XM_047422613.1 → XP_047278569.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  29. XM_047422612.1 → XP_047278568.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  30. XM_047422610.1 → XP_047278566.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  31. XM_047422615.1 → XP_047278571.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  32. XM_011518131.3 → XP_011516433.1  semaphorin-4D isoform X1

    See identical proteins and their annotated locations for XP_011516433.1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854
    UniProtKB/TrEMBL
    Q4LE41
    Conserved Domains (3) summary
    cd05873
    Location:559 → 645
    Ig_Sema4D_like; Immunoglobulin (Ig)-like domain of the class IV semaphorin Sema4D
    cd11259
    Location:31 → 501
    Sema_4D; The Sema domain, a protein interacting module, of semaphorin 4D (Sema4D, also known as CD100)
    smart00423
    Location:503 → 554
    PSI; domain found in Plexins, Semaphorins and Integrins

  33. XM_011518130.3 → XP_011516432.1  semaphorin-4D isoform X1

    See identical proteins and their annotated locations for XP_011516432.1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854
    UniProtKB/TrEMBL
    Q4LE41
    Related
    ENSP00000416523.1, ENST00000450295.5
    Conserved Domains (3) summary
    cd05873
    Location:559 → 645
    Ig_Sema4D_like; Immunoglobulin (Ig)-like domain of the class IV semaphorin Sema4D
    cd11259
    Location:31 → 501
    Sema_4D; The Sema domain, a protein interacting module, of semaphorin 4D (Sema4D, also known as CD100)
    smart00423
    Location:503 → 554
    PSI; domain found in Plexins, Semaphorins and Integrins

  34. XM_047422611.1 → XP_047278567.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  35. XM_047422618.1 → XP_047278574.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  36. XM_011518134.3 → XP_011516436.1  semaphorin-4D isoform X1

    See identical proteins and their annotated locations for XP_011516436.1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854
    UniProtKB/TrEMBL
    Q4LE41
    Conserved Domains (3) summary
    cd05873
    Location:559 → 645
    Ig_Sema4D_like; Immunoglobulin (Ig)-like domain of the class IV semaphorin Sema4D
    cd11259
    Location:31 → 501
    Sema_4D; The Sema domain, a protein interacting module, of semaphorin 4D (Sema4D, also known as CD100)
    smart00423
    Location:503 → 554
    PSI; domain found in Plexins, Semaphorins and Integrins

  37. XM_047422632.1 → XP_047278588.1  semaphorin-4D isoform X5

  38. XM_047422631.1 → XP_047278587.1  semaphorin-4D isoform X5

  39. XM_047422630.1 → XP_047278586.1  semaphorin-4D isoform X5

  40. XM_047422634.1 → XP_047278590.1  semaphorin-4D isoform X5

  41. XM_047422633.1 → XP_047278589.1  semaphorin-4D isoform X5

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    101524564..101662071 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054361747.1 → XP_054217722.1  semaphorin-4D isoform X3

  2. XM_054361744.1 → XP_054217719.1  semaphorin-4D isoform X3

  3. XM_054361740.1 → XP_054217715.1  semaphorin-4D isoform X2

  4. XM_054361743.1 → XP_054217718.1  semaphorin-4D isoform X2

  5. XM_054361742.1 → XP_054217717.1  semaphorin-4D isoform X2

  6. XM_054361741.1 → XP_054217716.1  semaphorin-4D isoform X2

  7. XM_054361748.1 → XP_054217723.1  semaphorin-4D isoform X3

  8. XM_054361746.1 → XP_054217721.1  semaphorin-4D isoform X3

  9. XM_054361745.1 → XP_054217720.1  semaphorin-4D isoform X3

  10. XM_054361749.1 → XP_054217724.1  semaphorin-4D isoform X4

    UniProtKB/TrEMBL
    E9PFD9

  11. XM_054361717.1 → XP_054217692.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  12. XM_054361724.1 → XP_054217699.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  13. XM_054361718.1 → XP_054217693.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  14. XM_054361730.1 → XP_054217705.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  15. XM_054361721.1 → XP_054217696.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  16. XM_054361728.1 → XP_054217703.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  17. XM_054361716.1 → XP_054217691.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  18. XM_054361719.1 → XP_054217694.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  19. XM_054361739.1 → XP_054217714.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  20. XM_054361738.1 → XP_054217713.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  21. XM_054361735.1 → XP_054217710.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  22. XM_054361731.1 → XP_054217706.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  23. XM_054361725.1 → XP_054217700.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  24. XM_054361737.1 → XP_054217712.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  25. XM_054361729.1 → XP_054217704.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  26. XM_054361723.1 → XP_054217698.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  27. XM_054361726.1 → XP_054217701.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  28. XM_054361722.1 → XP_054217697.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  29. XM_054361727.1 → XP_054217702.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  30. XM_054361736.1 → XP_054217711.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  31. XM_054361732.1 → XP_054217707.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  32. XM_054361733.1 → XP_054217708.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  33. XM_054361734.1 → XP_054217709.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  34. XM_054361720.1 → XP_054217695.1  semaphorin-4D isoform X1

    UniProtKB/Swiss-Prot
    B2RPM6, Q7Z5S4, Q8N8B0, Q92854

  35. XM_054361752.1 → XP_054217727.1  semaphorin-4D isoform X5

  36. XM_054361753.1 → XP_054217728.1  semaphorin-4D isoform X5

  37. XM_054361750.1 → XP_054217725.1  semaphorin-4D isoform X5

  38. XM_054361754.1 → XP_054217729.1  semaphorin-4D isoform X5

  39. XM_054361751.1 → XP_054217726.1  semaphorin-4D isoform X5

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_182635.1: Suppressed sequence

    Description
    NM_182635.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q92854.1 GenPept UniProtKB/Swiss-Prot:Q92854

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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