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odc1 ornithine decarboxylase 1 [ Danio rerio (zebrafish) ]

Gene ID: 114426, updated on 1-Jun-2024

Summary

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Official Symbol
odc1provided by ZNC
Official Full Name
ornithine decarboxylase 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-010816-1
See related
Ensembl:ENSDARG00000007377 AllianceGenome:ZFIN:ZDB-GENE-010816-1
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
odc; fc54f04; fi06d08; CHUNP6922; wu:fc54f04; wu:fi06d08
Summary
Predicted to enable ornithine decarboxylase activity. Acts upstream of or within eye photoreceptor cell development. Predicted to be active in cytoplasm. Is expressed in neuromast and ovary. Orthologous to several human genes including ODC1 (ornithine decarboxylase 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See odc1 in Genome Data Viewer
Location:
chromosome: 17
Exon count:
11
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (51743921..51757548)
105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (51654886..51668513)

Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene ATPase H+ transporting V1 subunit C2 Neighboring gene nucleolar protein 10 Neighboring gene si:ch211-168d23.3 Neighboring gene exonuclease 3'-5' domain containing 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Isolation and characterization of ornithine decarboxylase gene from flounder (Paralichthys olivaceus). Lee JH, et al. Mar Biotechnol (NY), 2004 Sep-Oct. PMID 15791490
  2. Regulation of ornithine decarboxylase by antizymes and antizyme inhibitor in zebrafish (Danio rerio). Hascilowicz T, et al. Biochim Biophys Acta, 2002 Oct 11. PMID 12393184
  3. RNA-seq analysis and compound screening highlight multiple signalling pathways regulating secondary cell death after acute CNS injury in vivo. Herzog C, et al. Biol Open, 2020 May 4. PMID 32366533, Free PMC Article
  4. Fluid dynamics during bleb formation in migrating cells in vivo. Goudarzi M, et al. PLoS One, 2019. PMID 30807602, Free PMC Article
  5. Zebrafish cdc25a is expressed during early development and limiting for post-blastoderm cell cycle progression. Nogare DE, et al. Dev Dyn, 2007 Dec. PMID 17969147, Free PMC Article

See all (61) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. molecular cloning of species-specific enzyme and its antizyme-mediated degradation
    Title: Regulation of ornithine decarboxylase by antizymes and antizyme inhibitor in zebrafish (Danio rerio).
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
  
enables ornithine decarboxylase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ornithine decarboxylase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within eye photoreceptor cell development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within polyamine biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in putrescine biosynthetic process from ornithine IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ornithine decarboxylase
NP_571876.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_131801.2 → NP_571876.1  ornithine decarboxylase

    See identical proteins and their annotated locations for NP_571876.1

    Status: PROVISIONAL

    Source sequence(s)
    AB069857
    UniProtKB/TrEMBL
    A0A2R8RVZ8, F8W5Z9, Q9DGJ4
    Related
    ENSDARP00000124918.1, ENSDART00000149039.3
    Conserved Domains (2) summary
    cd00622
    Location:37 → 409
    PLPDE_III_ODC; Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Ornithine Decarboxylase
    COG0019
    Location:40 → 409
    LysA; Diaminopimelate decarboxylase [Amino acid transport and metabolism]

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007128.7 Reference GRCz11 Primary Assembly

    Range
    51743921..51757548
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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