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cest-27 Carboxylic ester hydrolase [ Caenorhabditis elegans ]

Gene ID: 171610, updated on 2-Nov-2024

Summary

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Official Symbol
cest-27
Official Full Name
Carboxylic ester hydrolase
Primary source
WormBase:WBGene00018958
Locus tag
CELE_F56C11.6
See related
AllianceGenome:WB:WBGene00018958
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable carboxylic ester hydrolase activity. Human ortholog(s) of this gene implicated in colorectal cancer and gastrointestinal system cancer. Orthologous to human CES1 (carboxylesterase 1) and CES4A (carboxylesterase 4A). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See cest-27 in Genome Data Viewer
Location:
chromosome: I
Exon count:
8
Sequence:
Chromosome: I; NC_003279.8 (171340..175989)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Nematode cuticle collagen N-terminal domain-containing protein Neighboring gene Dual oxidase 1 Neighboring gene SSD domain-containing protein Neighboring gene ncRNA Neighboring gene MARVEL domain-containing protein Neighboring gene Sulfhydryl oxidase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of innate immunity genes and pathways using a comparative genomics approach. Alper S, et al. Proc Natl Acad Sci U S A, 2008 May 13. PMID 18463287, Free PMC Article
  2. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables carboxylic ester hydrolase activity IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Carboxylic ester hydrolase
NP_490688.1
  • Confirmed by transcript evidence
NP_871861.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    171340..175989
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_182061.6 → NP_871861.2  Carboxylic ester hydrolase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_871861.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q86S38
    Conserved Domains (1) summary
    pfam00135
    Location:29 → 548
    COesterase; Carboxylesterase family

  2. NM_058287.8 → NP_490688.1  Carboxylic ester hydrolase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_490688.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2L069
    Conserved Domains (2) summary
    COG0657
    Location:101 → 270
    Aes; Acetyl esterase/lipase [Lipid transport and metabolism]
    pfam00135
    Location:16 → 528
    COesterase; Carboxylesterase family

RNA

  1. NR_131341.1 RNA Sequence

    Status: REVIEWED

Nucleotide Protein
Heading Accession and Version

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