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chdp-1 Calponin homology domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 172326, updated on 2-Nov-2024

Summary

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Official Symbol
chdp-1
Official Full Name
Calponin homology domain-containing protein
Primary source
WormBase:WBGene00015687
Locus tag
CELE_C10G11.7
See related
AllianceGenome:WB:WBGene00015687
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in nervous system development. Predicted to be located in cell cortex; growth cone; and plasma membrane. Is expressed widely. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See chdp-1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
5
Sequence:
Chromosome: I; NC_003279.8 (6284973..6289340)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Verprolin-like Neighboring gene Pantothenate kinase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Calponin Family Member CHDP-1 Interacts with Rac/CED-10 to Promote Cell Protrusions. Guan L, et al. PLoS Genet, 2016 Jul. PMID 27415421, Free PMC Article
  2. Identification of muscle-specific regulatory modules in Caenorhabditis elegans. Zhao G, et al. Genome Res, 2007 Mar. PMID 17284674, Free PMC Article
  3. The cell cortex-localized protein CHDP-1 is required for dendritic development and transport in C. elegans neurons. Zhao T, et al. PLoS Genet, 2022 Sep. PMID 36126047, Free PMC Article
  4. Proteomic analysis of Caenorhabditis elegans. Jeong PY, et al. Methods Mol Biol, 2009. PMID 19381582
  5. Stable-isotope labeling with amino acids in nematodes. Larance M, et al. Nat Methods, 2011 Aug 28. PMID 21874007, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in nervous system development IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cell cortex IEA
Inferred from Electronic Annotation
more info
  
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in growth cone IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Calponin homology domain-containing protein
NP_491813.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    6284973..6289340
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059412.7 → NP_491813.1  Calponin homology domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491813.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P91027
    Conserved Domains (1) summary
    cd00014
    Location:123 → 243
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...

RNA

  1. NR_136357.1 RNA Sequence

    Status: REVIEWED

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P91027.1

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