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rpl35 ribosomal protein L35 [ Danio rerio (zebrafish) ]

Gene ID: 192299, updated on 12-Sep-2024

Summary

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Official Symbol
rpl35provided by ZNC
Official Full Name
ribosomal protein L35provided by ZNC
Primary source
ZFIN:ZDB-GENE-020419-2
See related
Ensembl:ENSDARG00000018334 AllianceGenome:ZFIN:ZDB-GENE-020419-2
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
CHUNP6863
Summary
Predicted to enable mRNA binding activity. Predicted to be a structural constituent of ribosome. Acts upstream of or within chordate embryonic development; erythrocyte differentiation; and regulation of cell cycle. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 19. Orthologous to human RPL35 (ribosomal protein L35). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See rpl35 in Genome Data Viewer
Location:
chromosome: 21
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (5873228..5881125, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (5766311..5774208, complement)

Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene proteinase-activated receptor 3 Neighboring gene WD repeat domain 38 Neighboring gene ubiquinol-cytochrome c reductase, complex III subunit X Neighboring gene proline dehydrogenase (oxidase) 1a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Identification of RECK as an evolutionarily conserved tumor suppressor gene for zebrafish malignant peripheral nerve sheath tumors. Kumari R, et al. Oncotarget, 2018 May 4. PMID 29805750, Free PMC Article
  2. RNA secondary structure profiling in zebrafish reveals unique regulatory features. Kaushik K, et al. BMC Genomics, 2018 Feb 15. PMID 29448945, Free PMC Article
  3. Ribosomal protein deficiency causes Tp53-independent erythropoiesis failure in zebrafish. Yadav GV, et al. Int J Biochem Cell Biol, 2014 Apr. PMID 24417973
  4. Subtractive phage display technology identifies zebrafish marcksb that is required for gastrulation. Wang YW, et al. Gene, 2013 May 25. PMID 23537994
  5. Mitochondrial Dysfunction, Disruption of F-Actin Polymerization, and Transcriptomic Alterations in Zebrafish Larvae Exposed to Trichloroethylene. Wirbisky SE, et al. Chem Res Toxicol, 2016 Feb 15. PMID 26745549

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within chordate embryonic development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within erythrocyte differentiation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of cell cycle IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within regulation of cell cycle IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic large ribosomal subunit IEA
Inferred from Electronic Annotation
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
large ribosomal subunit protein uL29
Names
60S ribosomal protein L35

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_173233.2 → NP_775340.1  large ribosomal subunit protein uL29

    See identical proteins and their annotated locations for NP_775340.1

    Status: PROVISIONAL

    Source sequence(s)
    EH554774
    UniProtKB/Swiss-Prot
    Q8JHJ1
    Related
    ENSDARP00000018594.7, ENSDART00000009241.10
    Conserved Domains (1) summary
    pfam00831
    Location:8 → 63
    Ribosomal_L29; Ribosomal L29 protein

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007132.7 Reference GRCz11 Primary Assembly

    Range
    5873228..5881125 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8JHJ1.3 GenPept UniProtKB/Swiss-Prot:Q8JHJ1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.