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dcun1d2a DCN1, defective in cullin neddylation 1, domain containing 2a [ Danio rerio (zebrafish) ]

Gene ID: 192303, updated on 28-Oct-2024

Summary

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Official Symbol
dcun1d2aprovided by ZNC
Official Full Name
DCN1, defective in cullin neddylation 1, domain containing 2aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-020416-2
See related
Ensembl:ENSDARG00000040838 AllianceGenome:ZFIN:ZDB-GENE-020416-2
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
cb191; rp42-pen; zgc:77887
Summary
Predicted to enable cullin family protein binding activity; ubiquitin conjugating enzyme binding activity; and ubiquitin-like protein binding activity. Predicted to be involved in protein neddylation. Predicted to be part of ubiquitin ligase complex. Is expressed in several structures, including adaxial cell; axis; lens; pectoral fin; and pharyngeal arch 3-7 skeleton. Orthologous to human DCUN1D2 (defective in cullin neddylation 1 domain containing 2). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
all
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Genomic context

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See dcun1d2a in Genome Data Viewer
Location:
chromosome: 9
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (34938316..34945582, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (35129131..35136416, complement)

Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene UPF3A regulator of nonsense mediated mRNA decay Neighboring gene cell division cycle 16 homolog (S. cerevisiae) Neighboring gene transcription factor Dp-1, a Neighboring gene methyltransferase 21C, AARS1 lysine b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Chaperone-Mediated Autophagy in the Light of Evolution: Insight from Fish. Lescat L, et al. Mol Biol Evol, 2020 Oct 1. PMID 32437540
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables cullin family protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ubiquitin conjugating enzyme binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ubiquitin-like protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in protein neddylation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
DCN1-like protein 2a
Names
rp42 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205538.1 → NP_991101.1  DCN1-like protein 2a

    See identical proteins and their annotated locations for NP_991101.1

    Status: PROVISIONAL

    Source sequence(s)
    BC065884
    UniProtKB/TrEMBL
    A0A8M1PCT2, Q6P007
    Related
    ENSDARP00000059860.5, ENSDART00000059861.7
    Conserved Domains (2) summary
    cd14412
    Location:2 → 48
    UBA_DCNL2; UBA-like domain found in DCN1-like protein 2 (DCNL2) and similar proteins
    pfam03556
    Location:136 → 246
    Cullin_binding; Cullin binding

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007120.7 Reference GRCz11 Primary Assembly

    Range
    34938316..34945582 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005167810.5 → XP_005167867.1  DCN1-like protein 2a isoform X1

    See identical proteins and their annotated locations for XP_005167867.1

    UniProtKB/TrEMBL
    A0A8M9Q4G8
    Related
    ENSDARP00000123371.1, ENSDART00000131908.3
    Conserved Domains (2) summary
    pfam03556
    Location:121 → 231
    Cullin_binding; Cullin binding
    cl21463
    Location:1 → 33
    UBA_like_SF; UBA domain-like superfamily

  2. XM_005167811.5 → XP_005167868.1  DCN1-like protein 2a isoform X1

    See identical proteins and their annotated locations for XP_005167868.1

    UniProtKB/TrEMBL
    A0A8M9Q4G8
    Related
    ENSDARP00000121805.1, ENSDART00000136812.2
    Conserved Domains (2) summary
    pfam03556
    Location:121 → 231
    Cullin_binding; Cullin binding
    cl21463
    Location:1 → 33
    UBA_like_SF; UBA domain-like superfamily

  3. XM_021478598.2 → XP_021334273.1  DCN1-like protein 2a isoform X1

    UniProtKB/TrEMBL
    A0A8M9Q4G8
    Conserved Domains (2) summary
    pfam03556
    Location:121 → 231
    Cullin_binding; Cullin binding
    cl21463
    Location:1 → 33
    UBA_like_SF; UBA domain-like superfamily

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394760.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    228987..236287 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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