ddx19b DEAD-box helicase 19b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ddx19bprovided by ZNC
Official Full Name: DEAD-box helicase 19bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-020419-30
See related: Ensembl:ENSDARG00000005699 AllianceGenome:ZFIN:ZDB-GENE-020419-30
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: ddx19; fi21a04; chunp6915; wu:fb24g07; wu:fc59e08; wu:fd14f03; wu:fi21a04
Summary: Predicted to enable RNA helicase activity and mRNA binding activity. Predicted to be involved in poly(A)+ mRNA export from nucleus. Predicted to be active in cytoplasmic stress granule and nucleus. Orthologous to several human genes including DDX19A (DEAD-box helicase 19A). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 11

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	11	NC_007122.7 (3524737..3535500, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	11	NC_007122.6 (3505350..3516113, complement)

Chromosome 11 - NC_007122.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fj79h12.y1 (e-PCR)
- UniSTS:199945

fb24g07.x1 (e-PCR)
- UniSTS:203090

fd14f03.x1 (e-PCR)
- UniSTS:204174

fi21a04.x1 (e-PCR)
- UniSTS:197014

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables RNA helicase activity	IBA Inferred from Biological aspect of Ancestor more info
enables RNA helicase activity	IEA Inferred from Electronic Annotation more info
enables helicase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables mRNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in poly(A)+ mRNA export from nucleus	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasmic stress granule	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: ATP-dependent RNA helicase DDX19B

Names: DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 19 (DBP5 homolog, yeast); DEAD/H box polypeptide 19

NP_775365.1

EC 3.6.4.13

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_173258.1 → NP_775365.1 ATP-dependent RNA helicase DDX19B

See identical proteins and their annotated locations for NP_775365.1

Status: PROVISIONAL

Source sequence(s)

AY099536

UniProtKB/TrEMBL

Q7ZU28, Q8JGR1

Related

ENSDARP00000003250.4, ENSDART00000009788.7

Conserved Domains (3) summary

PTZ00424
Location:99 → 477

PTZ00424; helicase 45; Provisional

cd00079
Location:315 → 450

HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...

cl21455
Location:102 → 304

P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases