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Rpl15 ribosomal protein L15 [ Rattus norvegicus (Norway rat) ]

Gene ID: 245981, updated on 2-May-2024

Summary

Official Symbol
Rpl15provided by RGD
Official Full Name
ribosomal protein L15provided by RGD
Primary source
RGD:621181
See related
Ensembl:ENSRNOG00000008140 AllianceGenome:RGD:621181
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Rpl10
Summary
Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Involved in response to ethanol. Located in A band. Part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 12. Orthologous to human RPL15 (ribosomal protein L15). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 1290.7), Spleen (RPKM 1283.5) and 9 other tissues See more
Orthologs
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Genomic context

See Rpl15 in Genome Data Viewer
Location:
15p16
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (9934663..9937946)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (7503883..7507166)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (8188717..8192153)

Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene ubiquitin-conjugating enzyme E2E 1 Neighboring gene uncharacterized protein DDB_G0290685-like Neighboring gene NFKB inhibitor interacting Ras-like 1 Neighboring gene nuclear receptor subfamily 1, group D, member 2 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase like 7

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
 
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in cytoplasmic translation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in response to ethanol IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in A band IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of cytosolic large ribosomal subunit IDA
Inferred from Direct Assay
more info
PubMed 
part_of cytosolic large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
 
located_in cytosolic ribosome IEA
Inferred from Electronic Annotation
more info
 
located_in cytosolic ribosome ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
part_of ribosomal subunit IEA
Inferred from Electronic Annotation
more info
 
is_active_in synapse ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
large ribosomal subunit protein eL15
Names
60S ribosomal protein L15

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_139114.3NP_620814.1  large ribosomal subunit protein eL15

    See identical proteins and their annotated locations for NP_620814.1

    Status: VALIDATED

    Source sequence(s)
    AA687059, BC078724
    UniProtKB/Swiss-Prot
    P61314
    UniProtKB/TrEMBL
    A0A8I6A471, A6K036
    Related
    ENSRNOP00000010759.3, ENSRNOT00000010759.7
    Conserved Domains (1) summary
    pfam00827
    Location:2191
    Ribosomal_L15e; Ribosomal L15

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086033.1 Reference GRCr8

    Range
    9934663..9937946
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)