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cbf12 DNA-binding transcription factor, CBF1/Su(H)/LAG-1 family Cbf12 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539119, updated on 22-Jun-2024

Summary

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Gene symbol
cbf12
Gene description
DNA-binding transcription factor, CBF1/Su(H)/LAG-1 family Cbf12
Locus tag
SPOM_SPCC1223.13
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Old locus tag
SPCC1223.13
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Genomic context

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See cbf12 in Genome Data Viewer
Location:
chromosome: III
Exon count:
1
Sequence:
Chromosome: III; NC_003421.2 (1871367..1875842)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene serine/threonine protein phosphatase PP2C catalytic subunit Ptc2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene GPI-anchored protein Meu10 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene chorismate synthase Neighboring gene calcium/calmodulin-dependent (CaMKK) protein kinase Ssp1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Fission yeast CSL proteins function as transcription factors. Oravcová M, et al. PLoS One, 2013. PMID 23555033, Free PMC Article
  2. N-termini of fungal CSL transcription factors are disordered, enriched in regulatory motifs and inhibit DNA binding in fission yeast. Převorovský M, et al. PLoS One, 2011. PMID 21858190, Free PMC Article
  3. Cbf11 and Cbf12, the fission yeast CSL proteins, play opposing roles in cell adhesion and coordination of cell and nuclear division. Prevorovský M, et al. Exp Cell Res, 2009 May 1. PMID 19101542
  4. Fission Yeast CSL Transcription Factors: Mapping Their Target Genes and Biological Roles. Převorovský M, et al. PLoS One, 2015. PMID 26366556, Free PMC Article
  5. Conserved and Diverged Functions of the Calcineurin-Activated Prz1 Transcription Factor in Fission Yeast. Chatfield-Reed K, et al. Genetics, 2016 Apr. PMID 26896331, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Results show that Cbf11 and Cbf12 bind to an overlapping set of target genes, including those with important roles in cell cycle regulation.
    Title: Fission Yeast CSL Transcription Factors: Mapping Their Target Genes and Biological Roles.
  2. Studies indicate that the Cbf11 and Cbf12 CSL paralogs play antagonistic roles in cell adhesion and the coordination of cell and nuclear division.
    Title: N-termini of fungal CSL transcription factors are disordered, enriched in regulatory motifs and inhibit DNA binding in fission yeast.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of flocculation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of chromatin IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
DNA-binding transcription factor, CBF1/Su(H)/LAG-1 family Cbf12

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    1871367..1875842
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001023349.3 → NP_588358.1  DNA-binding transcription factor, CBF1/Su(H)/LAG-1 family Cbf12 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_588358.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O74412
    Conserved Domains (2) summary
    pfam09270
    Location:631 → 825
    BTD; Beta-trefoil DNA-binding domain
    pfam09271
    Location:473 → 629
    LAG1-DNAbind; LAG1, DNA binding
Nucleotide Protein
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