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pcp1 gamma tubulin complex linker, pericentrin/kendrin Pcp1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541455, updated on 18-Sep-2024

Summary

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Official Symbol
pcp1
Official Full Name
gamma tubulin complex linker, pericentrin/kendrin Pcp1
Primary source
PomBase:SPAC6G9.06c
Locus tag
SPOM_SPAC6G9.06C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See pcp1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (3254401..3258280, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ArfGEF Spo7 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene coenzyme A diphosphatase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ARP2/3 actin-organizing complex subunit Arc4 Neighboring gene ubiquitin hydrolase Ubp6

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The core spindle pole body scaffold Ppc89 links the pericentrin orthologue Pcp1 to the fission yeast spindle pole body via an evolutionarily conserved interface. Chen JS, et al. Mol Biol Cell, 2024 Aug 1. PMID 38985524, Free PMC Article
  2. Pcp1p, an Spc110p-related calmodulin target at the centrosome of the fission yeast Schizosaccharomyces pombe. Flory MR, et al. Cell Growth Differ, 2002 Feb. PMID 11864908
  3. Spatiotemporal regulations of Wee1 at the G2/M transition. Masuda H, et al. Mol Biol Cell, 2011 Mar 1. PMID 21233285, Free PMC Article
  4. Fission yeast mutants affecting telomere clustering and meiosis-specific spindle pole body integrity. Jin Y, et al. Genetics, 2002 Mar. PMID 11901107, Free PMC Article
  5. An SMC-domain protein in fission yeast links telomeres to the meiotic centrosome. Flory MR, et al. Mol Cell, 2004 Nov 19. PMID 15546621

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The core spindle pole body scaffold Ppc89 links the pericentrin orthologue Pcp1 to the fission yeast spindle pole body via an evolutionarily conserved interface.
    Title: The core spindle pole body scaffold Ppc89 links the pericentrin orthologue Pcp1 to the fission yeast spindle pole body via an evolutionarily conserved interface.
  2. pericentrin-like Pcp1 regulates multiple functions of the spindle pole body (SPB) through recruiting two critical factors, the gamma-tubulin complex (gamma-TuC) and polo kinase (Plo1)
    Title: Fission yeast Pcp1 links polo kinase-mediated mitotic entry to gamma-tubulin-dependent spindle formation.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables spindle pole body anchor activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables spindle pole body anchor activity IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitotic spindle formation (spindle phase one) IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in central plaque of mitotic spindle pole body IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in meiotic spindle pole body IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in mitotic spindle pole body IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in new mitotic spindle pole body IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus leading edge IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
gamma tubulin complex linker, pericentrin/kendrin Pcp1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    3254401..3258280 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019539.3 → NP_594115.1  gamma tubulin complex linker, pericentrin/kendrin Pcp1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594115.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q92351
    Conserved Domains (5) summary
    COG1196
    Location:150 → 1010
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01496
    Location:545 → 636
    V_ATPase_I; V-type ATPase 116kDa subunit family
    pfam07989
    Location:152 → 219
    Cnn_1N; Centrosomin N-terminal motif 1
    pfam10495
    Location:1112 → 1186
    PACT_coil_coil; Pericentrin-AKAP-450 domain of centrosomal targeting protein
    cl19219
    Location:928 → 1017
    DUF342; Protein of unknown function (DUF342)
Nucleotide Protein
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