sebox SEBOX homeobox [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: seboxprovided by ZNC
Official Full Name: SEBOX homeoboxprovided by ZNC
Primary source: ZFIN:ZDB-GENE-021206-4
See related: Ensembl:ENSDARG00000042526 AllianceGenome:ZFIN:ZDB-GENE-021206-4
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: og9x
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within endoderm development; heart morphogenesis; and regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in margin; marginal blastomere; presumptive endoderm; and shield. Orthologous to human SEBOX (SEBOX homeobox). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 5

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	5	NC_007116.7 (67371412..67382183)
105	previous assembly	GRCz10 (GCF_000002035.5)	5	NC_007116.6 (66693281..66703814)

Chromosome 5 - NC_007116.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cell differentiation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within endoderm development	IDA Inferred from Direct Assay more info
acts_upstream_of_or_within heart morphogenesis	IGI Inferred from Genetic Interaction more info
acts_upstream_of_or_within regulation of DNA-templated transcription	IDA Inferred from Direct Assay more info
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: homeobox protein SEBOX

Names: OG9 homeobox; homeobox OG-9; homeobox transcription factor mezzo; mezzo; skin-, embryo-, brain- and oocyte-specific homeobox

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001320052.1 → NP_001306981.1 homeobox protein SEBOX

Status: VALIDATED

Source sequence(s)

BX957226

UniProtKB/Swiss-Prot

A2BIQ1, Q8JJ26

Related

ENSDARP00000113809.1, ENSDART00000142156.2

Conserved Domains (2) summary

COG5576
Location:13 → 159

COG5576; Homeodomain-containing transcription factor [Transcription]

pfam00046
Location:61 → 112

Homeobox; Homeobox domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007116.7 Reference GRCz11 Primary Assembly

Range

67371412..67382183

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_068221087.1 → XP_068077188.1 homeobox protein SEBOX isoform X1

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_173227.1: Suppressed sequence

Description

NM_173227.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.