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TRIQK triple QxxK/R motif containing [ Homo sapiens (human) ]

Gene ID: 286144, updated on 17-Sep-2024

Summary

Official Symbol
TRIQKprovided by HGNC
Official Full Name
triple QxxK/R motif containingprovided by HGNC
Primary source
HGNC:HGNC:27828
See related
Ensembl:ENSG00000205133 AllianceGenome:HGNC:27828
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C8orf83; PRO0845; UPF0599
Summary
Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal (RPKM 10.3), thyroid (RPKM 9.6) and 25 other tissues See more
Orthologs
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Genomic context

See TRIQK in Genome Data Viewer
Location:
8q22.1
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (92883534..93017665, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (94008453..94091047, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (93895762..93978372, complement)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC441369 Neighboring gene uncharacterized LOC124901978 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27616 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19356 Neighboring gene ReSE screen-validated silencer GRCh37_chr8:93986327-93986595 Neighboring gene interferon regulatory factor 5 pseudogene 1 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:94050860-94051674 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27617 Neighboring gene microRNA 8084 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr8:94146448-94147647 Neighboring gene long intergenic non-protein coding RNA 2906 Neighboring gene uncharacterized LOC105375644

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • FLJ40637, DKFZp779L1068

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
triple QxxK/R motif-containing protein
Names
protein TRIQK
triple repetitive-sequence of QXXK/R protein homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001171795.2NP_001165266.1  triple QxxK/R motif-containing protein

    See identical proteins and their annotated locations for NP_001165266.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1-7 all encode the same protein.
    Source sequence(s)
    BC110326, BQ009934, BX474727
    Consensus CDS
    CCDS55261.1
    UniProtKB/Swiss-Prot
    Q629K1
    Related
    ENSP00000430837.1, ENST00000518748.5
    Conserved Domains (1) summary
    pfam15168
    Location:152
    TRIQK; Triple QxxK/R motif-containing protein family
  2. NM_001171796.2NP_001165267.1  triple QxxK/R motif-containing protein

    See identical proteins and their annotated locations for NP_001165267.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1-7 all encode the same protein.
    Source sequence(s)
    BC031029, BC110326, BQ009934, DA093687
    Consensus CDS
    CCDS55261.1
    UniProtKB/Swiss-Prot
    Q629K1
    Related
    ENSP00000368138.5, ENST00000378861.9
    Conserved Domains (1) summary
    pfam15168
    Location:152
    TRIQK; Triple QxxK/R motif-containing protein family
  3. NM_001171797.2NP_001165268.1  triple QxxK/R motif-containing protein

    See identical proteins and their annotated locations for NP_001165268.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1-7 all encode the same protein.
    Source sequence(s)
    BC110326, BQ009934, DA093687, DQ351291
    Consensus CDS
    CCDS55261.1
    UniProtKB/Swiss-Prot
    Q629K1
    Related
    ENSP00000429517.1, ENST00000521988.6
    Conserved Domains (1) summary
    pfam15168
    Location:152
    TRIQK; Triple QxxK/R motif-containing protein family
  4. NM_001171798.2NP_001165269.1  triple QxxK/R motif-containing protein

    See identical proteins and their annotated locations for NP_001165269.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR, compared to variant 1. Variants 1-7 all encode the same protein.
    Source sequence(s)
    AK097956, BC110326, BQ009934, DA093687
    Consensus CDS
    CCDS55261.1
    UniProtKB/Swiss-Prot
    Q629K1
    Related
    ENSP00000428822.1, ENST00000520430.5
    Conserved Domains (1) summary
    pfam15168
    Location:152
    TRIQK; Triple QxxK/R motif-containing protein family
  5. NM_001171799.2NP_001165270.1  triple QxxK/R motif-containing protein

    See identical proteins and their annotated locations for NP_001165270.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR, compared to variant 1. Variants 1-7 all encode the same protein.
    Source sequence(s)
    BC110326, BQ009934, DA191587
    Consensus CDS
    CCDS55261.1
    UniProtKB/Swiss-Prot
    Q629K1
    Related
    ENSP00000442030.1, ENST00000537541.1
    Conserved Domains (1) summary
    pfam15168
    Location:152
    TRIQK; Triple QxxK/R motif-containing protein family
  6. NM_001191035.2NP_001177964.1  triple QxxK/R motif-containing protein

    See identical proteins and their annotated locations for NP_001177964.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR, compared to variant 1. Variants 1-7 all encode the same protein.
    Source sequence(s)
    AC027242, AC117834, BQ009934, CB989812
    Consensus CDS
    CCDS55261.1
    UniProtKB/Swiss-Prot
    Q629K1
    Related
    ENSP00000429742.1, ENST00000524107.5
    Conserved Domains (1) summary
    pfam15168
    Location:152
    TRIQK; Triple QxxK/R motif-containing protein family
  7. NM_001191036.2NP_001177965.1  triple QxxK/R motif-containing protein

    See identical proteins and their annotated locations for NP_001177965.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR, compared to variant 1. Variants 1-7 all encode the same protein.
    Source sequence(s)
    AC027242, AC117834, BQ009934, DA115453
    Consensus CDS
    CCDS55261.1
    UniProtKB/Swiss-Prot
    Q629K1
    Related
    ENSP00000429381.1, ENST00000519969.5
    Conserved Domains (1) summary
    pfam15168
    Location:152
    TRIQK; Triple QxxK/R motif-containing protein family

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

    Range
    92883534..93017665 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047421713.1XP_047277669.1  triple QxxK/R motif-containing protein isoform X1

    UniProtKB/Swiss-Prot
    Q629K1
  2. XM_017013350.2XP_016868839.1  triple QxxK/R motif-containing protein isoform X1

    UniProtKB/Swiss-Prot
    Q629K1
    Related
    ENSP00000430992.1, ENST00000521617.5
    Conserved Domains (1) summary
    pfam15168
    Location:152
    TRIQK; Triple QxxK/R motif-containing protein family
  3. XM_017013347.2XP_016868836.1  triple QxxK/R motif-containing protein isoform X1

    UniProtKB/Swiss-Prot
    Q629K1
    Conserved Domains (1) summary
    pfam15168
    Location:152
    TRIQK; Triple QxxK/R motif-containing protein family
  4. XM_047421711.1XP_047277667.1  triple QxxK/R motif-containing protein isoform X1

    UniProtKB/Swiss-Prot
    Q629K1
  5. XM_024447136.2XP_024302904.1  triple QxxK/R motif-containing protein isoform X1

    UniProtKB/Swiss-Prot
    Q629K1
    Conserved Domains (1) summary
    pfam15168
    Location:152
    TRIQK; Triple QxxK/R motif-containing protein family
  6. XM_047421712.1XP_047277668.1  triple QxxK/R motif-containing protein isoform X1

    UniProtKB/Swiss-Prot
    Q629K1
  7. XM_017013349.2XP_016868838.1  triple QxxK/R motif-containing protein isoform X1

    UniProtKB/Swiss-Prot
    Q629K1
    Conserved Domains (1) summary
    pfam15168
    Location:152
    TRIQK; Triple QxxK/R motif-containing protein family

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060932.1 Alternate T2T-CHM13v2.0

    Range
    94008453..94091047 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054360331.1XP_054216306.1  triple QxxK/R motif-containing protein isoform X1

    UniProtKB/Swiss-Prot
    Q629K1
  2. XM_054360327.1XP_054216302.1  triple QxxK/R motif-containing protein isoform X1

    UniProtKB/Swiss-Prot
    Q629K1
  3. XM_054360328.1XP_054216303.1  triple QxxK/R motif-containing protein isoform X1

    UniProtKB/Swiss-Prot
    Q629K1
  4. XM_054360330.1XP_054216305.1  triple QxxK/R motif-containing protein isoform X1

    UniProtKB/Swiss-Prot
    Q629K1
  5. XM_054360329.1XP_054216304.1  triple QxxK/R motif-containing protein isoform X1

    UniProtKB/Swiss-Prot
    Q629K1
  6. XM_054360332.1XP_054216307.1  triple QxxK/R motif-containing protein isoform X1

    UniProtKB/Swiss-Prot
    Q629K1