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ube2kb ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast) [ Danio rerio (zebrafish) ]

Gene ID: 30100, updated on 12-Sep-2024

Summary

Official Symbol
ube2kbprovided by ZNC
Official Full Name
ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast)provided by ZNC
Primary source
ZFIN:ZDB-GENE-980605-9
See related
Ensembl:ENSDARG00000013505 AllianceGenome:ZFIN:ZDB-GENE-980605-9
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
hip2; ube2k; zgc:103472
Summary
Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and protein polyubiquitination. Predicted to be active in nucleus. Is expressed in lens. Orthologous to human UBE2K (ubiquitin conjugating enzyme E2 K). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See ube2kb in Genome Data Viewer
Location:
chromosome: 1
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (23311617..23321800)
105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (22620878..22631061)

Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene UDP-glucose 6-dehydrogenase Neighboring gene small integral membrane protein 14 Neighboring gene PDS5 cohesin associated factor A Neighboring gene NEDD4 binding protein 2

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
enables ubiquitin conjugating enzyme activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ubiquitin conjugating enzyme activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in protein polyubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast)
Names
ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)
NP_001008611.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008611.2NP_001008611.1  ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast)

    See identical proteins and their annotated locations for NP_001008611.1

    Status: VALIDATED

    Source sequence(s)
    AL715279, BC086816, DN767847, EH554183, EH575297
    UniProtKB/TrEMBL
    A0A0A0MPF4, A0A8N7XJ58, F6NKK5, Q5PR60
    Related
    ENSDARP00000120324.1, ENSDART00000139003.2

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007112.7 Reference GRCz11 Primary Assembly

    Range
    23311617..23321800
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394481.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    47087..57270
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)