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Mrpl30 mitochondrial ribosomal protein L30 [ Rattus norvegicus (Norway rat) ]

Gene ID: 301352, updated on 25-Jul-2024

Summary

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Symbol
Mrpl30provided by RGD
Full Name
mitochondrial ribosomal protein L30provided by RGD
Primary source
RGD:1308196
See related
EnsemblRapid:ENSRNOG00000049330 AllianceGenome:RGD:1308196
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be part of mitochondrial large ribosomal subunit. Predicted to be active in mitochondrion. Orthologous to human MRPL30 (mitochondrial ribosomal protein L30). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Heart (RPKM 94.9), Muscle (RPKM 78.7) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Mrpl30 in Genome Data Viewer
Location:
9q21
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (47621226..47631986)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (40125352..40136189)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (44483809..44496116)

Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene lipoyltransferase 1 Neighboring gene microtubule interacting and trafficking domain containing 1 Neighboring gene lysozyme G2 Neighboring gene lysozyme G1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Mammalian mitochondrial ribosomal proteins. N-terminal amino acid sequencing, characterization, and identification of corresponding gene sequences. Goldschmidt-Reisin S, et al. J Biol Chem, 1998 Dec 25. PMID 9857009
  2. Structures of the human mitochondrial ribosome in native states of assembly. Brown A, et al. Nat Struct Mol Biol, 2017 Oct. PMID 28892042, Free PMC Article
  3. Structure of the large ribosomal subunit from human mitochondria. Brown A, et al. Science, 2014 Nov 7. PMID 25278503, Free PMC Article
  4. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
  5. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, et al. Nature, 2004 Apr 1. PMID 15057822

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of large ribosomal subunit IEA
Inferred from Electronic Annotation
more info
  
part_of mitochondrial large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
part_of mitochondrial large ribosomal subunit ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
large ribosomal subunit protein uL30m
Names
39S ribosomal protein L30, mitochondrial
39S ribosomal protein L30, mitochondrial-like
L30mt
MRP-L30

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106903.2 → NP_001100373.1  large ribosomal subunit protein uL30m precursor

    See identical proteins and their annotated locations for NP_001100373.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009
    UniProtKB/Swiss-Prot
    P0C2C1
    UniProtKB/TrEMBL
    A0A8L2R012, B5DEY4
    Related
    ENSRNOP00000067807.3, ENSRNOT00000075242.4
    Conserved Domains (1) summary
    cd01658
    Location:67 → 120
    Ribosomal_L30; Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that ...

  2. NM_001431990.1 → NP_001418919.1  large ribosomal subunit protein uL30m precursor

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086027.1 Reference GRCr8

    Range
    47621226..47631986
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008767056.4 → XP_008765278.1  large ribosomal subunit protein uL30m isoform X1

    See identical proteins and their annotated locations for XP_008765278.1

    UniProtKB/Swiss-Prot
    P0C2C1
    UniProtKB/TrEMBL
    A0A8L2R012, B5DEY4
    Conserved Domains (1) summary
    cd01658
    Location:67 → 120
    Ribosomal_L30; Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that ...

  2. XM_039083224.2 → XP_038939152.1  large ribosomal subunit protein uL30m isoform X1

    UniProtKB/Swiss-Prot
    P0C2C1
    UniProtKB/TrEMBL
    A0A8L2R012, B5DEY4
    Related
    ENSRNOP00000083246.1, ENSRNOT00000110341.2
    Conserved Domains (1) summary
    cd01658
    Location:67 → 120
    Ribosomal_L30; Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that ...
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P0C2C1.1 GenPept UniProtKB/Swiss-Prot:P0C2C1

Gene LinkOut

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