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hoxa2b homeobox A2b [ Danio rerio (zebrafish) ]

Gene ID: 30325, updated on 27-Mar-2024

Summary

Official Symbol
hoxa2bprovided by ZNC
Official Full Name
homeobox A2bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-990415-98
See related
Ensembl:ENSDARG00000023031 AllianceGenome:ZFIN:ZDB-GENE-990415-98
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
Z-75; hoxa2
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of transcription, DNA-templated. Predicted to be active in nucleus. Is expressed in several structures, including hindbrain; hindbrain neural keel; hindbrain neural plate; neural crest; and pharyngeal arch. Orthologous to human HOXA2 (homeobox A2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See hoxa2b in Genome Data Viewer
Location:
chromosome: 16
Exon count:
2
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (20926673..20929067)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (21120854..21123248)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101886298 Neighboring gene microRNA 196d Neighboring gene homeobox A9b Neighboring gene src kinase associated phosphoprotein 2 Neighboring gene sorting nexin 10b

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
homeobox protein Hox-A2b
Names
etID309949.16
homeo box A2b
homeobox gene A-2
hox-A2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_131106.1NP_571181.1  homeobox protein Hox-A2b

    See identical proteins and their annotated locations for NP_571181.1

    Status: PROVISIONAL

    Source sequence(s)
    AF307010
    UniProtKB/Swiss-Prot
    O42365, Q4PRA7, Q9DEZ0
    UniProtKB/TrEMBL
    B3DGA4
    Related
    ENSDARP00000023072.6, ENSDART00000009827.7
    Conserved Domains (1) summary
    pfam00046
    Location:137189
    Homeobox; Homeobox domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    20926673..20929067
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)