csnk2a2a casein kinase 2, alpha prime polypeptide a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: csnk2a2aprovided by ZNC
Official Full Name: casein kinase 2, alpha prime polypeptide aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-990415-28
See related: Ensembl:ENSDARG00000012818 AllianceGenome:ZFIN:ZDB-GENE-990415-28
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: ck2a2; ck2a2a; wu:fi09h12
Summary: Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; and regulation of chromosome separation. Predicted to act upstream of or within protein phosphorylation. Predicted to be part of protein kinase CK2 complex. Predicted to be active in cytosol and nucleus. Orthologous to human CSNK2A2 (casein kinase 2 alpha 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 7

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	7	NC_007118.7 (56751746..56766967, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	7	NC_007118.6 (56450335..56465556, complement)

Chromosome 7 - NC_007118.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

X99964 (e-PCR)
- UniSTS:205339

fi09h12.x1 (e-PCR)
- UniSTS:196753

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables kinase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables protein kinase activity	IEA Inferred from Electronic Annotation more info
enables protein serine/threonine kinase activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in DNA damage response	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within phosphorylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein phosphorylation	IEA Inferred from Electronic Annotation more info
involved_in regulation of chromosome separation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
part_of protein kinase CK2 complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: casein kinase 2, alpha prime polypeptide a

Names: casein kinase 2 alpha 2; casein kinase 2 alpha 2a; ck2 alpha'; etID309898.7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_131240.1 → NP_571315.1 casein kinase 2, alpha prime polypeptide a

See identical proteins and their annotated locations for NP_571315.1

Status: PROVISIONAL

Source sequence(s)

X99964

UniProtKB/TrEMBL

Q90457

Related

ENSDARP00000027027.6, ENSDART00000020967.7

Conserved Domains (2) summary

cd14132
Location:21 → 325

STKc_CK2_alpha; Catalytic subunit (alpha) of the Serine/Threonine Kinase, Casein Kinase 2

pfam00069
Location:39 → 324

Pkinase; Protein kinase domain