ldb2b LIM domain binding 2b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ldb2bprovided by ZNC
Official Full Name: LIM domain binding 2bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-990415-137
See related: Ensembl:ENSDARG00000034896 AllianceGenome:ZFIN:ZDB-GENE-990415-137
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: ldb3; ldb2l; zgc:92548; wu:fd16f11
Summary: Predicted to enable LIM domain binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; nervous system development; and positive regulation of transcription by RNA polymerase II. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in fin bud; head; paraxial mesoderm; spinal cord neural tube; and telencephalon. Orthologous to human LDB2 (LIM domain binding 2). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 1

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	1	NC_007112.7 (22805398..22834824, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	1	NC_007112.6 (22114659..22144108, complement)

Chromosome 1 - NC_007112.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fd36c08.x1 (e-PCR)
- UniSTS:195416

ldb3 (e-PCR)
- UniSTS:186982

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables LIM domain binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in negative regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in nervous system development	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
part_of transcription regulator complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: LIM domain-binding protein 2b

Names: LIM-domain binding factor 2 like; LIM-domain binding factor 2b; LIM-domain binding factor 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_131315.3 → NP_571390.1 LIM domain-binding protein 2b

See identical proteins and their annotated locations for NP_571390.1

Status: VALIDATED

Source sequence(s)

BX908795

UniProtKB/TrEMBL

B2GPU2, O73714

Related

ENSDARP00000043555.4, ENSDART00000043556.5

Conserved Domains (1) summary

pfam01803
Location:31 → 232

LIM_bind; LIM-domain binding protein

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007112.7 Reference GRCz11 Primary Assembly

Range

22805398..22834824 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_009307714.4 → XP_009305989.1 LIM domain-binding protein 2b isoform X1

UniProtKB/TrEMBL

A0A8M3BEY1

Conserved Domains (1) summary

pfam01803
Location:31 → 232

LIM_bind; LIM-domain binding protein
XM_009307716.4 → XP_009305991.1 LIM domain-binding protein 2b isoform X2

UniProtKB/TrEMBL

A0A8M3AZJ2

Conserved Domains (1) summary

pfam01803
Location:31 → 232

LIM_bind; LIM-domain binding protein