mtnr1bb melatonin receptor 1Bb [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: mtnr1bbprovided by ZNC
Official Full Name: melatonin receptor 1Bbprovided by ZNC
Primary source: ZFIN:ZDB-GENE-990415-156
See related: Ensembl:ENSDARG00000086493 AllianceGenome:ZFIN:ZDB-GENE-990415-156
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: mel1br; Mel1b-1; mel-1B-R; mtnr1br-2; mel-1B-R-B
Summary: Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within rhythmic process and signal transduction. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in caudal tuberal nucleus; dorsal caudal thalamic nucleus; periventricular grey zone; periventricular nucleus; and periventricular nucleus of caudal tuberculum. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human MTNR1B (melatonin receptor 1B). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 10

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	10	NC_007121.7 (25035459..25069155, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	10	NC_007121.6 (25066007..25099703, complement)

Chromosome 10 - NC_007121.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info
enables melatonin receptor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within rhythmic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: melatonin receptor type 1B-B

Names: mel1b receptor B; melatonin receptor 1B b; melatonin receptor Mel1b Z2.6-4; melatonin receptor type 1B z2.6; zMel1b-1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

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These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.