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Ubqln3 ubiquilin 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 308905, updated on 2-Nov-2024

Summary

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Official Symbol
Ubqln3provided by RGD
Official Full Name
ubiquilin 3provided by RGD
Primary source
RGD:1304920
See related
EnsemblRapid:ENSRNOG00000023833 AllianceGenome:RGD:1304920
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable polyubiquitin modification-dependent protein binding activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be active in cytosol. Orthologous to human UBQLN3 (ubiquilin 3). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Restricted expression toward (RPKM 510.9) See more
Orthologs
human all
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Genomic context

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See Ubqln3 in Genome Data Viewer
Location:
1q32
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (168016508..168019201, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (158604629..158607318, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (169331457..169334120, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134485159 Neighboring gene ubiquilin 5 Neighboring gene ubiquilin-like Neighboring gene olfactomedin 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables polyubiquitin modification-dependent protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ubiquilin-3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107543.2 → NP_001101013.1  ubiquilin-3

    See identical proteins and their annotated locations for NP_001101013.1

    Status: PROVISIONAL

    Source sequence(s)
    BC161885
    UniProtKB/TrEMBL
    B1WBT8
    Conserved Domains (4) summary
    smart00727
    Location:189 → 233
    STI1; Heat shock chaperonin-binding motif
    smart00213
    Location:22 → 92
    UBQ; Ubiquitin homologues
    cd14399
    Location:615 → 652
    UBA_PLICs; UBA domain of eukaryotic protein linking integrin-associated protein (IAP, also known as CD47) with cytoskeleton (PLIC) proteins
    cl00155
    Location:22 → 92
    UBQ; Ubiquitin-like proteins

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    168016508..168019201 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063262967.1 → XP_063119037.1  ubiquilin-3 isoform X3

  2. XM_039078150.2 → XP_038934078.1  ubiquilin-3 isoform X2

    Conserved Domains (2) summary
    cd01808
    Location:43 → 115
    Ubl_PLICs; ubiquitin-like (Ubl) domain found in eukaryotic protein linking integrin-associated protein (IAP, also known as CD47) with cytoskeleton (PLIC) proteins
    cl17974
    Location:218 → 258
    STI1; STI1 domain

  3. XM_017589198.2 → XP_017444687.1  ubiquilin-3 isoform X1

    UniProtKB/TrEMBL
    F7EYK8
    Related
    ENSRNOP00000034011.5, ENSRNOT00000032587.6
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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