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Kbtbd3 kelch repeat and BTB domain containing 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 315394, updated on 17-Aug-2024

Summary

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Official Symbol
Kbtbd3provided by RGD
Official Full Name
kelch repeat and BTB domain containing 3provided by RGD
Primary source
RGD:1310895
See related
EnsemblRapid:ENSRNOG00000069206 AllianceGenome:RGD:1310895
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Orthologous to human KBTBD3 (kelch repeat and BTB domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Heart (RPKM 45.4), Kidney (RPKM 43.2) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
8q11
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (9749229..9780036)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (1464162..1491144)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (1450345..1477250)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene MLV-related proviral Env polyprotein-like, pseudogene 5 Neighboring gene aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase Neighboring gene zinc finger protein 431 like, pseudogene 4 Neighboring gene Myb/SANT DNA binding domain containing 4 with coiled-coils

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

General protein information

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Preferred Names
kelch repeat and BTB domain-containing protein 3
Names
kelch repeat and BTB (POZ) domain containing 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108121.2 → NP_001101591.1  kelch repeat and BTB domain-containing protein 3

    See identical proteins and their annotated locations for NP_001101591.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000008
    UniProtKB/TrEMBL
    A6KQJ4, D4A7F5
    Conserved Domains (3) summary
    PHA03098
    Location:38 → 595
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:330 → 385
    Kelch; KELCH repeat [structural motif]
    cd18271
    Location:24 → 153
    BTB_POZ_KBTBD3_BKLHD3; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch repeat and BTB domain-containing protein 3 (KBTBD3)

  2. NM_001433311.1 → NP_001420240.1  kelch repeat and BTB domain-containing protein 3

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000008

  3. NM_001433312.1 → NP_001420241.1  kelch repeat and BTB domain-containing protein 3

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000008

  4. NM_001433313.1 → NP_001420242.1  kelch repeat and BTB domain-containing protein 3

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000008

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    9749229..9780036
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006242474.5 → XP_006242536.1  kelch repeat and BTB domain-containing protein 3 isoform X1

    UniProtKB/TrEMBL
    A6KQJ4, D4A7F5
    Related
    ENSRNOP00000085465.1, ENSRNOT00000120313.2
    Conserved Domains (3) summary
    PHA03098
    Location:38 → 595
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:330 → 385
    Kelch; KELCH repeat [structural motif]
    cd18271
    Location:24 → 153
    BTB_POZ_KBTBD3_BKLHD3; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch repeat and BTB domain-containing protein 3 (KBTBD3)

  2. XM_006242478.5 → XP_006242540.1  kelch repeat and BTB domain-containing protein 3 isoform X2

    Conserved Domains (6) summary
    smart00612
    Location:325 → 375
    Kelch; Kelch domain
    PHA03098
    Location:16 → 520
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:255 → 310
    Kelch; KELCH repeat [structural motif]
    pfam00651
    Location:1 → 67
    BTB; BTB/POZ domain
    pfam01344
    Location:464 → 507
    Kelch_1; Kelch motif
    pfam07707
    Location:75 → 176
    BACK; BTB And C-terminal Kelch

  3. XM_006242477.5 → XP_006242539.1  kelch repeat and BTB domain-containing protein 3 isoform X1

    See identical proteins and their annotated locations for XP_006242539.1

    UniProtKB/TrEMBL
    A6KQJ4, D4A7F5
    Conserved Domains (3) summary
    PHA03098
    Location:38 → 595
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:330 → 385
    Kelch; KELCH repeat [structural motif]
    cd18271
    Location:24 → 153
    BTB_POZ_KBTBD3_BKLHD3; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch repeat and BTB domain-containing protein 3 (KBTBD3)

  4. XM_006242476.4 → XP_006242538.1  kelch repeat and BTB domain-containing protein 3 isoform X1

    UniProtKB/TrEMBL
    A6KQJ4, D4A7F5
    Conserved Domains (3) summary
    PHA03098
    Location:38 → 595
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:330 → 385
    Kelch; KELCH repeat [structural motif]
    cd18271
    Location:24 → 153
    BTB_POZ_KBTBD3_BKLHD3; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch repeat and BTB domain-containing protein 3 (KBTBD3)

  5. XM_039081335.2 → XP_038937263.1  kelch repeat and BTB domain-containing protein 3 isoform X1

    UniProtKB/TrEMBL
    A6KQJ4, D4A7F5
    Conserved Domains (3) summary
    PHA03098
    Location:38 → 595
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:330 → 385
    Kelch; KELCH repeat [structural motif]
    cd18271
    Location:24 → 153
    BTB_POZ_KBTBD3_BKLHD3; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch repeat and BTB domain-containing protein 3 (KBTBD3)

  6. XM_039081336.2 → XP_038937264.1  kelch repeat and BTB domain-containing protein 3 isoform X1

    UniProtKB/TrEMBL
    A6KQJ4, D4A7F5
    Conserved Domains (3) summary
    PHA03098
    Location:38 → 595
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:330 → 385
    Kelch; KELCH repeat [structural motif]
    cd18271
    Location:24 → 153
    BTB_POZ_KBTBD3_BKLHD3; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch repeat and BTB domain-containing protein 3 (KBTBD3)
Nucleotide Protein Strain
Heading Accession and Version

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