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neff1 neuronal intermediate filament family member 1 [ Danio rerio (zebrafish) ]

Gene ID: 321113, updated on 2-Nov-2024

Summary

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Official Symbol
neff1provided by ZNC
Official Full Name
neuronal intermediate filament family member 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-9669
See related
Ensembl:ENSDARG00000012281 AllianceGenome:ZFIN:ZDB-GENE-030131-9669
Gene type
protein coding
RefSeq status
PREDICTED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
Ina; cb126; sb:cb126; zgc:65851
Summary
Predicted to enable structural molecule activity. Predicted to be located in intermediate filament. Is expressed in nervous system and neural tube. [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See neff1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (13671614..13684777, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (13171397..13184560, complement)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene purine-rich element binding protein Ba Neighboring gene H2A.Z variant histone 2a Neighboring gene MAX dimerization protein 1 Neighboring gene uncharacterized LOC137495562 Neighboring gene small nuclear ribonucleoprotein 27 (U4/U6.U5)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Developmental pattern of the neuronal intermediate filament inaa in the zebrafish retina. Liao ML, et al. J Comp Neurol, 2016 Dec 15. PMID 27159642
  2. Integrated analyses of zebrafish miRNA and mRNA expression profiles identify miR-29b and miR-223 as potential regulators of optic nerve regeneration. Fuller-Carter PI, et al. BMC Genomics, 2015 Aug 12. PMID 26265132, Free PMC Article
  3. Molecular analyses of zebrafish V0v spinal interneurons and identification of transcriptional regulators downstream of Evx1 and Evx2 in these cells. England SJ, et al. Neural Dev, 2023 Nov 28. PMID 38017520, Free PMC Article
  4. Proteomic profile of zebrafish brain based on two-dimensional gel electrophoresis matrix-assisted laser desorption/ionization MS/MS analysis. Singh SK, et al. Zebrafish, 2010 Jun. PMID 20528263
  5. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in intermediate filament IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC321113
Names
internexin neuronal intermediate filament protein, alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199534.1 → NP_955828.1  uncharacterized protein LOC321113

    See identical proteins and their annotated locations for NP_955828.1

    Status: PREDICTED

    Source sequence(s)
    BC056314
    UniProtKB/TrEMBL
    F6NKW3, Q6NZX1, Q7SZP4
    Related
    ENSDARP00000012500.6, ENSDART00000018351.7
    Conserved Domains (3) summary
    pfam00038
    Location:95 → 405
    Filament; Intermediate filament protein
    pfam04732
    Location:8 → 94
    Filament_head; Intermediate filament head (DNA binding) region
    pfam07798
    Location:311 → 400
    DUF1640; Protein of unknown function (DUF1640)

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    13671614..13684777 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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