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frmd6 FERM domain containing 6 [ Danio rerio (zebrafish) ]

Gene ID: 321937, updated on 2-Nov-2024

Summary

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Official Symbol
frmd6provided by ZNC
Official Full Name
FERM domain containing 6provided by ZNC
Primary source
ZFIN:ZDB-GENE-050522-354
See related
Ensembl:ENSDARG00000002332 AllianceGenome:ZFIN:ZDB-GENE-050522-354
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
wu:fb38g08; zgc:110114
Summary
Predicted to be involved in positive regulation of hippo signaling. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasmic side of apical plasma membrane. Orthologous to human FRMD6 (FERM domain containing 6). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See frmd6 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (36958086..36995448)
105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (36832196..36869558)

Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene tripartite motif containing 9 Neighboring gene thioredoxin-related transmembrane protein 1 Neighboring gene uncharacterized LOC137487339 Neighboring gene estrogen receptor 2b Neighboring gene spectrin repeat containing, nuclear envelope 2b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Disruption of Trim9 function abrogates macrophage motility in vivo. Tokarz DA, et al. J Leukoc Biol, 2017 Dec. PMID 29021367, Free PMC Article
  2. Control of tissue growth by Yap relies on cell density and F-actin in zebrafish fin regeneration. Mateus R, et al. Development, 2015 Aug 15. PMID 26209644, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in developmental process IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of hippo signaling IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasmic side of apical plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
FERM domain-containing protein 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001020816.1 → NP_001018652.1  FERM domain-containing protein 6

    See identical proteins and their annotated locations for NP_001018652.1

    Status: PROVISIONAL

    Source sequence(s)
    BC095176
    UniProtKB/TrEMBL
    Q503U6
    Related
    ENSDARP00000024425.8, ENSDART00000024386.11
    Conserved Domains (4) summary
    smart00295
    Location:20 → 215
    B41; Band 4.1 homologues
    cd13185
    Location:219 → 327
    FERM_C_FRMD1_FRMD6; FERM domain C-lobe of FERM domain containing 1 and 6 proteins
    pfam00373
    Location:115 → 226
    FERM_M; FERM central domain
    pfam09379
    Location:20 → 82
    FERM_N; FERM N-terminal domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007124.7 Reference GRCz11 Primary Assembly

    Range
    36958086..36995448
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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