dnajc3a DnaJ (Hsp40) homolog, subfamily C, member 3a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: dnajc3aprovided by ZNC
Official Full Name: DnaJ (Hsp40) homolog, subfamily C, member 3aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-1264
See related: Ensembl:ENSDARG00000041110 AllianceGenome:ZFIN:ZDB-GENE-030131-1264
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: dnajc3; zgc:56356; zgc:77731; wu:fb64f06
Summary: Predicted to enable chaperone binding activity and misfolded protein binding activity. Predicted to be involved in protein folding in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including axis; digestive system; hatching gland; periderm; and polster. Orthologous to human DNAJC3 (DnaJ heat shock protein family (Hsp40) member C3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 9

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	9	NC_007120.7 (29484046..29497885, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	9	NC_007120.6 (29673300..29687139, complement)

Chromosome 9 - NC_007120.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

AI496855 (e-PCR)
- UniSTS:206396

fb63f06.y1 (e-PCR)
- UniSTS:190902

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables misfolded protein binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein-folding chaperone binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in protein folding in endoplasmic reticulum	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within response to unfolded protein	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in endoplasmic reticulum	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: dnaJ homolog subfamily C member 3a

Names: DnaJ (Hsp40) homolog, subfamily C, member 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_199610.2 → NP_955904.2 dnaJ homolog subfamily C member 3a

See identical proteins and their annotated locations for NP_955904.2

Status: PROVISIONAL

Source sequence(s)

BC065443

UniProtKB/TrEMBL

A0A8M1PD52, Q6P0U6

Related

ENSDARP00000060245.3, ENSDART00000060246.4

Conserved Domains (6) summary

COG0484
Location:391 → 502

DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]

TIGR02552
Location:262 → 389

LcrH_SycD; type III secretion low calcium response chaperone LcrH/SycD

sd00006
Location:37 → 65

TPR; TPR repeat [structural motif]

pfam00226
Location:394 → 459

DnaJ; DnaJ domain

pfam00515
Location:73 → 104

TPR_1; Tetratricopeptide repeat

pfam13414
Location:38 → 102

TPR_11; TPR repeat