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stx5al syntaxin 5A, like [ Danio rerio (zebrafish) ]

Gene ID: 323105, updated on 17-Sep-2024

Summary

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Official Symbol
stx5alprovided by ZNC
Official Full Name
syntaxin 5A, likeprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-1825
See related
Ensembl:ENSDARG00000003175 AllianceGenome:ZFIN:ZDB-GENE-030131-1825
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:73276; wu:fb81g12
Summary
Predicted to enable SNAP receptor activity and SNARE binding activity. Predicted to be involved in several processes, including endoplasmic reticulum to Golgi vesicle-mediated transport; vesicle docking; and vesicle fusion. Predicted to act upstream of or within vesicle-mediated transport. Predicted to be located in membrane. Predicted to be part of SNARE complex. Predicted to be active in Golgi membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See stx5al in Genome Data Viewer
Location:
chromosome: 21
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (26536950..26554327)
105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (26502418..26517632)

Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene adenylosuccinate synthase, like Neighboring gene vascular endothelial growth factor Bb Neighboring gene protein RD3 Neighboring gene potassium channel subfamily K member 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. The BH3-only SNARE BNip1 mediates photoreceptor apoptosis in response to vesicular fusion defects. Nishiwaki Y, et al. Dev Cell, 2013 May 28. PMID 23725763
  2. The Evolution of Duplicated Genes of the Cpi-17/Phi-1 (ppp1r14) Family of Protein Phosphatase 1 Inhibitors in Teleosts. Lang I, et al. Int J Mol Sci, 2020 Aug 9. PMID 32784920, Free PMC Article
  3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables SNAP receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables SNARE binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in vesicle docking IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in vesicle fusion IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of SNARE complex IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in endomembrane system IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
syntaxin 5A, like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199630.2 → NP_955924.2  syntaxin 5A, like

    Status: VALIDATED

    Source sequence(s)
    CR631122
    UniProtKB/TrEMBL
    A0A8M1PD64, Q6PBS1
    Related
    ENSDARP00000114359.1, ENSDART00000146315.3
    Conserved Domains (2) summary
    cd15844
    Location:258 → 343
    SNARE_syntaxin5; SNARE motif of syntaxin 5
    pfam11416
    Location:49 → 69
    Syntaxin-5_N; Syntaxin-5 N-terminal, Sly1p-binding domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007132.7 Reference GRCz11 Primary Assembly

    Range
    26536950..26554327
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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