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pou2f1b POU class 2 homeobox 1b [ Danio rerio (zebrafish) ]

Gene ID: 323702, updated on 28-Oct-2024

Summary

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Official Symbol
pou2f1bprovided by ZNC
Official Full Name
POU class 2 homeobox 1bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-2422
See related
Ensembl:ENSDARG00000007996 AllianceGenome:ZFIN:ZDB-GENE-030131-2422
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fc07d06; wu:fc07d06; zgc:158360
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in telencephalon. Orthologous to human POU2F1 (POU class 2 homeobox 1). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
human mouse all
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Genomic context

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See pou2f1b in Genome Data Viewer
Location:
chromosome: 9
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (34319333..34355548)
105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (34510148..34546363)

Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene immunoglobulin-like domain containing receptor 2 Neighboring gene glycoprotein A33 (transmembrane), paralog b Neighboring gene uncharacterized LOC137496486 Neighboring gene CD247 antigen like Neighboring gene uncharacterized LOC101887113

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Structural characteristics of zebrafish orthologs of adaptor molecules that associate with transmembrane immune receptors. Yoder JA, et al. Gene, 2007 Oct 15. PMID 17719728, Free PMC Article
  2. Evolutionary context can clarify gene names: Teleosts as a case study. Gasanov EV, et al. Bioessays, 2021 Jun. PMID 33829511
  3. YTHDF2-mediated regulations bifurcate BHPF-induced programmed cell deaths. Lin J, et al. Natl Sci Rev, 2023 Dec. PMID 38152479, Free PMC Article
  4. Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches. Diotel N, et al. J Comp Neurol, 2015 Jun 1. PMID 25556858, Free PMC Article
  5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
POU domain, class 2, transcription factor 1b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001089329.1 → NP_001082798.1  POU domain, class 2, transcription factor 1b

    See identical proteins and their annotated locations for NP_001082798.1

    Status: PROVISIONAL

    Source sequence(s)
    BC134808
    UniProtKB/TrEMBL
    A4IFW4
    Related
    ENSDARP00000037034.6, ENSDART00000035522.8
    Conserved Domains (2) summary
    smart00352
    Location:214 → 287
    POU; Found in Pit-Oct-Unc transcription factors
    pfam00046
    Location:321 → 375
    Homeobox; Homeobox domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007120.7 Reference GRCz11 Primary Assembly

    Range
    34319333..34355548
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005167815.4 → XP_005167872.1  POU domain, class 2, transcription factor 1b isoform X4

    UniProtKB/TrEMBL
    A0A8M2BFW2
    Conserved Domains (3) summary
    smart00352
    Location:236 → 310
    POU; Found in Pit-Oct-Unc transcription factors
    pfam00046
    Location:340 → 394
    Homeobox; Homeobox domain
    pfam03153
    Location:59 → 226
    TFIIA; Transcription factor IIA, alpha/beta subunit

  2. XM_009304814.3 → XP_009303089.1  POU domain, class 2, transcription factor 1b isoform X7

    UniProtKB/TrEMBL
    A0A8M3AW75
    Conserved Domains (3) summary
    smart00352
    Location:236 → 310
    POU; Found in Pit-Oct-Unc transcription factors
    pfam00046
    Location:340 → 394
    Homeobox; Homeobox domain
    pfam03153
    Location:59 → 226
    TFIIA; Transcription factor IIA, alpha/beta subunit

  3. XM_005167816.4 → XP_005167873.1  POU domain, class 2, transcription factor 1b isoform X6

    UniProtKB/TrEMBL
    A0A8M2BF85
    Conserved Domains (3) summary
    smart00352
    Location:236 → 310
    POU; Found in Pit-Oct-Unc transcription factors
    pfam00046
    Location:340 → 393
    Homeobox; Homeobox domain
    pfam03153
    Location:59 → 226
    TFIIA; Transcription factor IIA, alpha/beta subunit

  4. XM_017357651.3 → XP_017213140.1  POU domain, class 2, transcription factor 1b isoform X8

    UniProtKB/TrEMBL
    A0A8M6Z2I0

  5. XM_068223294.1 → XP_068079395.1  POU domain, class 2, transcription factor 1b isoform X1

  6. XM_068223297.1 → XP_068079398.1  POU domain, class 2, transcription factor 1b isoform X5

  7. XM_068223296.1 → XP_068079397.1  POU domain, class 2, transcription factor 1b isoform X3

  8. XM_068223299.1 → XP_068079400.1  POU domain, class 2, transcription factor 1b isoform X10

  9. XM_068223298.1 → XP_068079399.1  POU domain, class 2, transcription factor 1b isoform X9

  10. XM_068223295.1 → XP_068079396.1  POU domain, class 2, transcription factor 1b isoform X2

Nucleotide Protein Strain
Heading Accession and Version

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