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cstf1 cleavage stimulation factor, 3' pre-RNA, subunit 1 [ Danio rerio (zebrafish) ]

Gene ID: 324238, updated on 2-Nov-2024

Summary

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Official Symbol
cstf1provided by ZNC
Official Full Name
cleavage stimulation factor, 3' pre-RNA, subunit 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-2958
See related
Ensembl:ENSDARG00000044820 AllianceGenome:ZFIN:ZDB-GENE-030131-2958
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fc22d10; zgc:66207; zgc:77560; wu:fc22d10; wu:fd16h09
Summary
Predicted to act upstream of or within mRNA 3'-end processing. Predicted to be part of mRNA cleavage stimulating factor complex. Orthologous to human CSTF1 (cleavage stimulation factor subunit 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See cstf1 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (27817301..27827533, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (27570127..27580359, complement)

Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137496702 Neighboring gene uncharacterized LOC137496653 Neighboring gene eukaryotic translation initiation factor 4 gamma, 3a Neighboring gene endothelin converting enzyme 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within mRNA 3'-end processing IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of mRNA cleavage stimulating factor complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mRNA cleavage stimulating factor complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
cleavage stimulation factor subunit 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001328559.1 → NP_001315488.1  cleavage stimulation factor subunit 1

    Status: VALIDATED

    Source sequence(s)
    BX601648, EH556892, EH592404
    UniProtKB/TrEMBL
    A0A8M1P431, F1QFK9
    Related
    ENSDARP00000111131.1, ENSDART00000130800.4
    Conserved Domains (4) summary
    COG2319
    Location:104 → 428
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:100 → 424
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    pfam16699
    Location:6 → 62
    CSTF1_dimer; Cleavage stimulation factor subunit 1, dimerization domain
    sd00039
    Location:116 → 171
    7WD40; WD40 repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007122.7 Reference GRCz11 Primary Assembly

    Range
    27817301..27827533 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_212670.1: Suppressed sequence

    Description
    NM_212670.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein Strain
Heading Accession and Version

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