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rbbp8l retinoblastoma binding protein 8-like [ Danio rerio (zebrafish) ]

Gene ID: 324358, updated on 17-Aug-2024

Summary

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Official Symbol
rbbp8lprovided by ZNC
Official Full Name
retinoblastoma binding protein 8-likeprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-3078
See related
Ensembl:ENSDARG00000087032 AllianceGenome:ZFIN:ZDB-GENE-030131-3078
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fc26f04; wu:fc26f04; si:ch211-200e2.1
Summary
Predicted to enable DNA binding activity. Predicted to be involved in DNA double-strand break processing involved in repair via single-strand annealing and double-strand break repair via homologous recombination. Predicted to be active in site of double-strand break. Orthologous to human RBBP8NL (RBBP8 N-terminal like). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See rbbp8l in Genome Data Viewer
Location:
chromosome: 23
Exon count:
17
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (7467446..7501955)
105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (7536613..7567987)

Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene si:dkeyp-73a2.2 Neighboring gene GATA binding protein 5 Neighboring gene HCK proto-oncogene, Src family tyrosine kinase Neighboring gene transmembrane 9 superfamily protein member 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Evolution and genomic organization of muscle microRNAs in fish genomes. Nachtigall PG, et al. BMC Evol Biol, 2014 Sep 25. PMID 25253178, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables damaged DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in DNA double-strand break processing involved in repair via single-strand annealing IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
RBBP8 N-terminal-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007134.7 Reference GRCz11 Primary Assembly

    Range
    7467446..7501955
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005174119.4 → XP_005174176.1  RBBP8 N-terminal-like protein

    See identical proteins and their annotated locations for XP_005174176.1

    UniProtKB/TrEMBL
    A0A8M2BLD6, E7F5C4, F1QUK9
    Related
    ENSDARP00000122644.2, ENSDART00000135551.4
    Conserved Domains (1) summary
    pfam10482
    Location:6 → 124
    CtIP_N; Tumour-suppressor protein CtIP N-terminal domain

RNA

  1. XR_002456555.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials