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eif3ea eukaryotic translation initiation factor 3, subunit E, a [ Danio rerio (zebrafish) ]

Gene ID: 325102, updated on 12-Sep-2024

Summary

Official Symbol
eif3eaprovided by ZNC
Official Full Name
eukaryotic translation initiation factor 3, subunit E, aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-3827
See related
Ensembl:ENSDARG00000090697 AllianceGenome:ZFIN:ZDB-GENE-030131-3827
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
eif3s6; eif3s6a; fc55e01; eIF3-p48; zgc:63821; wu:fc55e01
Summary
Predicted to contribute to translation initiation factor activity. Acts upstream of or within camera-type eye development; embryonic viscerocranium morphogenesis; and pigmentation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 3 complex. Predicted to be active in nucleus. Is expressed in ceratobranchial cartilage; eye; female organism; and gut. Orthologous to human EIF3E (eukaryotic translation initiation factor 3 subunit E). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See eif3ea in Genome Data Viewer
Location:
chromosome: 16
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (38556846..38629126, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (38606814..38679094, complement)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene CD83 molecule Neighboring gene R-spondin 2 Neighboring gene ER membrane protein complex subunit 2 Neighboring gene uncharacterized LOC137487849

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Markers

Clone Names

  • MGC63821

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables translation initiation factor activity IEA
Inferred from Electronic Annotation
more info
 
contributes_to translation initiation factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within camera-type eye development IMP
Inferred from Mutant Phenotype
more info
 
acts_upstream_of_or_within embryonic viscerocranium morphogenesis IMP
Inferred from Mutant Phenotype
more info
 
involved_in formation of cytoplasmic translation initiation complex IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within pigmentation IMP
Inferred from Mutant Phenotype
more info
 
acts_upstream_of_or_within translation IEA
Inferred from Electronic Annotation
more info
 
involved_in translational initiation IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within translational initiation IEA
Inferred from Electronic Annotation
more info
 
involved_in translational initiation ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
part_of eukaryotic 43S preinitiation complex IEA
Inferred from Electronic Annotation
more info
 
part_of eukaryotic 48S preinitiation complex IEA
Inferred from Electronic Annotation
more info
 
part_of eukaryotic translation initiation factor 3 complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of eukaryotic translation initiation factor 3 complex IEA
Inferred from Electronic Annotation
more info
 
part_of eukaryotic translation initiation factor 3 complex ISS
Inferred from Sequence or Structural Similarity
more info
 
part_of eukaryotic translation initiation factor 3 complex, eIF3e IEA
Inferred from Electronic Annotation
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
eukaryotic translation initiation factor 3 subunit E-A
Names
eukaryotic translation initiation factor 3, subunit 6a
int6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200839.1NP_957133.1  eukaryotic translation initiation factor 3 subunit E-A

    See identical proteins and their annotated locations for NP_957133.1

    Status: PROVISIONAL

    Source sequence(s)
    BC061454
    UniProtKB/Swiss-Prot
    Q1LUA7, Q1LUA8, Q6DRI1, Q6P7X8, Q6TH16
    Related
    ENSDARP00000106853.2, ENSDART00000126705.4
    Conserved Domains (2) summary
    pfam01399
    Location:291395
    PCI; PCI domain
    pfam09440
    Location:5138
    eIF3_N; eIF3 subunit 6 N terminal domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    38556846..38629126 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394970.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    292488..364505 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)