kdelr2b KDEL endoplasmic reticulum protein retention receptor 2b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: kdelr2bprovided by ZNC
Official Full Name: KDEL endoplasmic reticulum protein retention receptor 2bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-4189
See related: Ensembl:ENSDARG00000037361 AllianceGenome:ZFIN:ZDB-GENE-030131-4189
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: kdelr2l; zgc:66047; wu:fa93g04; wu:fc79e05
Summary: Predicted to enable ER retention sequence binding activity. Predicted to be involved in protein retention in ER lumen. Predicted to act upstream of or within protein transport. Predicted to be located in COPI-coated vesicle membrane; Golgi membrane; and endoplasmic reticulum membrane. Predicted to be active in cis-Golgi network and endoplasmic reticulum. Is expressed in ectoderm; epidermis; notochord; otic vesicle; and splanchnocranium. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 21. Orthologous to human KDELR2 (KDEL endoplasmic reticulum protein retention receptor 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 12

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	12	NC_007123.7 (982858..990058, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	12	NC_007123.6 (947271..954471, complement)

Chromosome 12 - NC_007123.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ER retention sequence binding	IBA Inferred from Biological aspect of Ancestor more info
enables ER retention sequence binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in protein retention in ER lumen	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within protein retention in ER lumen	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in COPI-coated vesicle membrane	IEA Inferred from Electronic Annotation more info
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info
is_active_in cis-Golgi network	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasmic vesicle	IEA Inferred from Electronic Annotation more info
is_active_in endoplasmic reticulum	IBA Inferred from Biological aspect of Ancestor more info
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ER lumen protein-retaining receptor 2b

Names: KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2, like; KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.