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esf1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) [ Danio rerio (zebrafish) ]

Gene ID: 326718, updated on 12-Sep-2024

Summary

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Official Symbol
esf1provided by ZNC
Official Full Name
ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-4917
See related
Ensembl:ENSDARG00000008740 AllianceGenome:ZFIN:ZDB-GENE-030131-4917
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fe06g12; zgc:66241; im:7138472; wu:fe06g12
Summary
Predicted to enable RNA binding activity. Acts upstream of or within neural crest cell development; pharyngeal system development; and rRNA processing. Predicted to be located in nucleolus. Is expressed in several structures, including digestive system; head; immature eye; midbrain neural rod; and pectoral fin bud. Orthologous to human ESF1 (ESF1 nucleolar pre-rRNA processing protein homolog). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See esf1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (51202984..51219965, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (50559185..50576166, complement)

Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene jagged canonical Notch ligand 1a Neighboring gene BTB (POZ) domain containing 3a Neighboring gene NADH:ubiquinone oxidoreductase complex assembly factor 5 Neighboring gene kinesin family member 16Ba

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. The Progress of CRISPR/Cas9-Mediated Gene Editing in Generating Mouse/Zebrafish Models of Human Skeletal Diseases. Wu N, et al. Comput Struct Biotechnol J, 2019. PMID 31360334, Free PMC Article
  2. The ribosome biogenesis protein Esf1 is essential for pharyngeal cartilage formation in zebrafish. Chen JY, et al. FEBS J, 2018 Sep. PMID 30073783
  3. A Toolbox for Efficient Proximity-Dependent Biotinylation in Zebrafish Embryos. Rosenthal SM, et al. Mol Cell Proteomics, 2021. PMID 34332124, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within neural crest cell development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within pharyngeal system development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in rRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within rRNA processing IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within rRNA processing IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ESF1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199745.2 → NP_956039.2  ESF1 homolog

    Status: PROVISIONAL

    Source sequence(s)
    CU138540
    UniProtKB/TrEMBL
    A0A8M1PBS9, B8JKQ1
    Related
    ENSDARP00000113328.1, ENSDART00000146612.2
    Conserved Domains (2) summary
    COG5638
    Location:8 → 719
    COG5638; Uncharacterized conserved protein [Function unknown]
    pfam08159
    Location:661 → 689
    NUC153; NUC153 domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007112.7 Reference GRCz11 Primary Assembly

    Range
    51202984..51219965 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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