exosc6 exosome component 6 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: exosc6provided by ZNC
Official Full Name: exosome component 6provided by ZNC
Primary source: ZFIN:ZDB-GENE-050522-362
See related: Ensembl:ENSDARG00000036060 AllianceGenome:ZFIN:ZDB-GENE-050522-362
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:77314; id:ibd1130; wu:fe17d05; zgc:110071
Summary: Predicted to enable RNA binding activity. Predicted to be involved in RNA metabolic process. Predicted to act upstream of or within rRNA processing. Predicted to be located in cytoplasm and nucleus. Predicted to be part of cytoplasmic exosome (RNase complex) and nuclear exosome (RNase complex). Predicted to be active in nucleolus. Is expressed in forebrain; hindbrain; immature eye; midbrain; and optic tectum. Orthologous to human EXOSC6 (exosome component 6). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 7

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	7	NC_007118.7 (29163791..29164805, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	7	NC_007118.6 (28892641..28893655, complement)

Chromosome 7 - NC_007118.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables RNA binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in U4 snRNA 3'-end processing	IBA Inferred from Biological aspect of Ancestor more info
involved_in nuclear mRNA surveillance	IBA Inferred from Biological aspect of Ancestor more info
involved_in poly(A)-dependent snoRNA 3'-end processing	IBA Inferred from Biological aspect of Ancestor more info
involved_in rRNA catabolic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within rRNA processing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
part_of cytoplasmic exosome (RNase complex)	IBA Inferred from Biological aspect of Ancestor more info
part_of exosome (RNase complex)	IEA Inferred from Electronic Annotation more info
part_of exosome (RNase complex)	ISS Inferred from Sequence or Structural Similarity more info
part_of nuclear exosome (RNase complex)	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleolus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: exosome complex component MTR3

Names: mRNA transport regulator 3 homolog

NP_001018322.1

EC 3.1.13.-

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001020486.1 → NP_001018322.1 exosome complex component MTR3

See identical proteins and their annotated locations for NP_001018322.1

Status: PROVISIONAL

Source sequence(s)

BC095173

UniProtKB/Swiss-Prot

Q503U8, Q6P0I8

UniProtKB/TrEMBL

B2GQ67

Related

ENSDARP00000052347.4, ENSDART00000052348.6

Conserved Domains (2) summary

TIGR02065
Location:30 → 258

ECX1; archaeal exosome-like complex exonuclease 1

cd11371
Location:42 → 258

RNase_PH_MTR3; MTR3 subunit of eukaryotic exosome