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cnn3a calponin 3, acidic a [ Danio rerio (zebrafish) ]

Gene ID: 326931, updated on 12-Sep-2024

Summary

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Official Symbol
cnn3aprovided by ZNC
Official Full Name
calponin 3, acidic aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-5130
See related
Ensembl:ENSDARG00000099510 AllianceGenome:ZFIN:ZDB-GENE-030131-5130
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
cnn3; zgc:64211; wu:fe49h10
Summary
Predicted to enable actin binding activity and calmodulin binding activity. Predicted to act upstream of or within actomyosin structure organization. Predicted to be active in cytoskeleton. Is expressed in several structures, including cardiovascular system; head mesenchyme; intermediate cell mass of mesoderm; mesoderm; and notochord. Orthologous to human CNN3 (calponin 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See cnn3a in Genome Data Viewer
Location:
chromosome: 24
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (31170362..31194816, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (31233151..31257605, complement)

Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene holocytochrome c synthase b Neighboring gene TLC domain containing 4a Neighboring gene ALG14 UDP-N-acetylglucosaminyltransferase subunit Neighboring gene coagulation factor IIIa

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Multiple bioanalytical method to reveal developmental biological responses in zebrafish embryos exposed to triclocarban. Dong X, et al. Chemosphere, 2018 Feb. PMID 29136572
  2. Acute and long-term metabolic consequences of early developmental Bisphenol A exposure in zebrafish (Danio rerio). Martínez R, et al. Chemosphere, 2020 Oct. PMID 32450349
  3. Evolution of the vertebrate paralemmin gene family: ancient origin of gene duplicates suggests distinct functions. Hultqvist G, et al. PLoS One, 2012. PMID 22855693, Free PMC Article
  4. Hepatic gene expression profiling using GeneChips in zebrafish exposed to 17alpha-methyldihydrotestosterone. Hoffmann JL, et al. Aquat Toxicol, 2008 Apr 28. PMID 18339436
  5. Zebrafish miR-1 and miR-133 shape muscle gene expression and regulate sarcomeric actin organization. Mishima Y, et al. Genes Dev, 2009 Mar 1. PMID 19240126, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
  
enables actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in actin filament organization IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within actomyosin structure organization IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in actin cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
calponin-3a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199753.1 → NP_956047.1  calponin-3a

    See identical proteins and their annotated locations for NP_956047.1

    Status: PROVISIONAL

    Source sequence(s)
    BC053309
    UniProtKB/TrEMBL
    A0A8M1PA43, Q7T303
    Related
    ENSDARP00000131550.1, ENSDART00000158808.2
    Conserved Domains (3) summary
    COG5199
    Location:27 → 188
    SCP1; Calponin [Cytoskeleton]
    pfam00307
    Location:29 → 125
    CH; Calponin homology (CH) domain
    pfam00402
    Location:164 → 187
    Calponin; Calponin family repeat

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007135.7 Reference GRCz11 Primary Assembly

    Range
    31170362..31194816 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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