slc16a3b solute carrier family 16 member 3b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: slc16a3bprovided by ZNC
Official Full Name: solute carrier family 16 member 3bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-5487
See related: Ensembl:ENSDARG00000045051 AllianceGenome:ZFIN:ZDB-GENE-030131-5487
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: MCT4b; slc16a3; zgc:55905; wu:fd20b02; wu:fi38f12
Summary: Predicted to enable monocarboxylic acid transmembrane transporter activity. Predicted to be involved in monocarboxylic acid transport. Predicted to act upstream of or within transmembrane transport. Predicted to be located in membrane. Predicted to be integral component of plasma membrane. Is expressed in several structures, including axis; cardiovascular system; muscle; nervous system; and primordial germ cell. Orthologous to human SLC16A3 (solute carrier family 16 member 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 12

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	12	NC_007123.7 (33350255..33359651, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	12	NC_007123.6 (33249272..33258743, complement)

Chromosome 12 - NC_007123.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Data indicate that monocarboxylate transporters (MCTs1-4) were all found to be expressed in brains of embryos, and were localized in both neurons and astrocyte.
Title: Spatial expression and functional flexibility of monocarboxylate transporter isoforms in the zebrafish brain.

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

AW171284 (e-PCR)
- UniSTS:205838

fd20b02.x1 (e-PCR)
- UniSTS:204264

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables lactate:proton symporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables monocarboxylic acid transmembrane transporter activity	IEA Inferred from Electronic Annotation more info
enables transmembrane transporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within monocarboxylic acid transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in basolateral plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

Go to the top of the page Help

Preferred Names: monocarboxylate transporter 4

Names: MCT4; monocarboxylate transporter 4b; solute carrier family 16 (monocarboxylate transporter), member 3; solute carrier family 16 (monocarboxylic acid transporters), member 3; solute carrier family 16 member 3

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_212708.1 → NP_997873.1 monocarboxylate transporter 4

See identical proteins and their annotated locations for NP_997873.1

Status: PROVISIONAL

Source sequence(s)

BC045489

UniProtKB/TrEMBL

Q7ZVM2

Related

ENSDARP00000066232.4, ENSDART00000066233.6

Conserved Domains (2) summary

cd06174
Location:22 → 410

MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...

pfam07690
Location:25 → 376

MFS_1; Major Facilitator Superfamily

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007123.7 Reference GRCz11 Primary Assembly

Range

33350255..33359651 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005169469.5 → XP_005169526.1 monocarboxylate transporter 4 isoform X1

UniProtKB/TrEMBL

A0A8M2BGR7, F1Q7T3

Related

ENSDARP00000000985.8, ENSDART00000001907.10

Conserved Domains (2) summary

cd06174
Location:22 → 410

MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...

pfam07690
Location:25 → 376

MFS_1; Major Facilitator Superfamily