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acin1b apoptotic chromatin condensation inducer 1b [ Danio rerio (zebrafish) ]

Gene ID: 327495, updated on 17-Aug-2024

Summary

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Official Symbol
acin1bprovided by ZNC
Official Full Name
apoptotic chromatin condensation inducer 1bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030826-12
See related
Ensembl:ENSDARG00000026842 AllianceGenome:ZFIN:ZDB-GENE-030826-12
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
acinus; acinusb; fi14c05; wu:fe06a10; wu:fi14c05
Summary
Predicted to enable nucleic acid binding activity. Orthologous to human ACIN1 (apoptotic chromatin condensation inducer 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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Location:
chromosome: 7
Exon count:
18
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (24069328..24097012)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (23798167..23825102)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene dehydrogenase/reductase (SDR family) member 4 Neighboring gene embryonal Fyn-associated substrate Neighboring gene ajuba LIM protein Neighboring gene mitochondrial ribosomal protein L52

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. MNK2 deficiency potentiates β-cell regeneration via translational regulation. Karampelias C, et al. Nat Chem Biol, 2022 Sep. PMID 35697798, Free PMC Article
  2. Genes with homology to mammalian apoptosis regulators identified in zebrafish. Inohara N, et al. Cell Death Differ, 2000 May. PMID 10917738
  3. Processing of fish Ig heavy chain transcripts: diverse splicing patterns and unusual nonsense mediated decay. Quiniou SM, et al. Dev Comp Immunol, 2011 Sep. PMID 21168434
  4. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
  5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in RNA splicing IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of ASAP complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
apoptotic chromatin condensation inducer 1b; apoptotic chromatin condensation inducer in the nucleus
Names
apoptotic chromatin condensation inducer in the nucleus, b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001305582.1 → NP_001292511.1  apoptotic chromatin condensation inducer 1b

    Status: VALIDATED

    Source sequence(s)
    CR388231, CT027785
    UniProtKB/TrEMBL
    A0A8M1P1U4, F1Q511
    Related
    ENSDARP00000029637.6, ENSDART00000034218.9
    Conserved Domains (3) summary
    cd12432
    Location:912 → 998
    RRM_ACINU; RNA recognition motif in apoptotic chromatin condensation inducer in the nucleus (acinus) and similar proteins
    pfam02037
    Location:14 → 48
    SAP; SAP domain
    pfam16294
    Location:1122 → 1157
    RSB_motif; RNSP1-SAP18 binding (RSB) motif

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    24069328..24097012
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021477409.1 → XP_021333084.1  apoptotic chromatin condensation inducer in the nucleus isoform X1

    UniProtKB/TrEMBL
    A0A8M9Q7J4
    Conserved Domains (3) summary
    cd12432
    Location:265 → 351
    RRM_ACINU; RNA recognition motif in apoptotic chromatin condensation inducer in the nucleus (acinus) and similar proteins
    pfam16294
    Location:475 → 510
    RSB_motif; RNSP1-SAP18 binding (RSB) motif
    cl28310
    Location:495 → 611
    Rho; Transcription termination factor Rho [Transcription]

  2. XM_021477410.1 → XP_021333085.1  apoptotic chromatin condensation inducer in the nucleus isoform X2

    UniProtKB/TrEMBL
    A0A8M9QGN5
    Conserved Domains (3) summary
    cd12432
    Location:212 → 298
    RRM_ACINU; RNA recognition motif in apoptotic chromatin condensation inducer in the nucleus (acinus) and similar proteins
    pfam16294
    Location:422 → 457
    RSB_motif; RNSP1-SAP18 binding (RSB) motif
    cl28310
    Location:442 → 558
    Rho; Transcription termination factor Rho [Transcription]

RNA

  1. XR_224930.4 RNA Sequence

  2. XR_002459127.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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