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arl8 ADP-ribosylation factor-like 8 [ Danio rerio (zebrafish) ]

Gene ID: 327551, updated on 12-Sep-2024

Summary

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Official Symbol
arl8provided by ZNC
Official Full Name
ADP-ribosylation factor-like 8provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-5762
See related
Ensembl:ENSDARG00000094709 AllianceGenome:ZFIN:ZDB-GENE-030131-5762
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
arl8l; zgc:55350; wu:fi17a05
Summary
Predicted to enable GTP binding activity. Predicted to be involved in intracellular protein transport; protein localization to Golgi membrane; and vesicle-mediated transport. Predicted to be active in trans-Golgi network. Orthologous to human ARL5B (ADP ribosylation factor like GTPase 5B). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See arl8 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (41713921..41726427, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (41433848..41446354, complement)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene MAM and LDL receptor class A domain containing 1 Neighboring gene uncharacterized LOC137496191 Neighboring gene histamine receptor H3 Neighboring gene VPS35 retromer complex component

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables GTP binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein localization to Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in trans-Golgi network IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ADP-ribosylation factor-like 8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199824.1 → NP_956118.1  ADP-ribosylation factor-like 8

    See identical proteins and their annotated locations for NP_956118.1

    Status: PROVISIONAL

    Source sequence(s)
    BC052766
    UniProtKB/TrEMBL
    Q7SZE7
    Related
    ENSDARP00000089895.4, ENSDART00000099121.7
    Conserved Domains (2) summary
    cd04153
    Location:3 → 175
    Arl5_Arl8; Arf-like 5 (Arl5) and 8 (Arl8) GTPases
    smart00178
    Location:8 → 173
    SAR; Sar1p-like members of the Ras-family of small GTPases

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    41713921..41726427 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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