U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

olfm2a olfactomedin 2a [ Danio rerio (zebrafish) ]

Gene ID: 334035, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
olfm2aprovided by ZNC
Official Full Name
olfactomedin 2aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2882
See related
Ensembl:ENSDARG00000077847 AllianceGenome:ZFIN:ZDB-GENE-040426-2882
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
olfm2; zgc:55410; wu:fi27g06; wu:fi30a05
Summary
Acts upstream of or within neural crest cell development. Predicted to be located in synapse. Predicted to be active in extracellular space. Is expressed in several structures, including midbrain neural tube; nervous system; optic cup; optic vesicle; and pancreatic system. Orthologous to human OLFM2 (olfactomedin 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See olfm2a in Genome Data Viewer
Location:
chromosome: 3
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (54012739..54237561)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (53758076..53982911)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene retinol dehydrogenase 8a Neighboring gene uncharacterized LOC137490778 Neighboring gene collagen, type V, alpha 3a Neighboring gene uncharacterized LOC137490169 Neighboring gene thyroid hormone receptor interactor 10a

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Olfactomedin-2 mediates development of the anterior central nervous system and head structures in zebrafish. Lee JA, et al. Mech Dev, 2008 Jan-Feb. PMID 18037275, Free PMC Article
  2. Cellular expression of Smarca4 (Brg1)-regulated genes in zebrafish retinas. Hensley MR, et al. BMC Dev Biol, 2011 Jul 14. PMID 21756345, Free PMC Article
  3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within neural crest cell development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in synapse IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
noelin-2a
Names
olfactomedin 2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_212717.1 → NP_997882.1  noelin-2a

    See identical proteins and their annotated locations for NP_997882.1

    Status: PROVISIONAL

    Source sequence(s)
    BC044164
    UniProtKB/TrEMBL
    Q803W5
    Related
    ENSDARP00000129003.2, ENSDART00000154542.3
    Conserved Domains (2) summary
    pfam02191
    Location:189 → 433
    OLF; Olfactomedin-like domain
    pfam12308
    Location:13 → 111
    Noelin-1; Neurogenesis glycoprotein

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    54012739..54237561
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009299770.4 → XP_009298045.1  noelin-2a isoform X2

    UniProtKB/TrEMBL
    A0A286Y8W4, A0A8M3AR74
    Related
    ENSDARP00000143588.1, ENSDART00000178486.2
    Conserved Domains (2) summary
    pfam02191
    Location:199 → 443
    OLF; Olfactomedin-like domain
    pfam12308
    Location:23 → 121
    Noelin-1; Neurogenesis glycoprotein

  2. XM_005163746.5 → XP_005163803.1  noelin-2a isoform X1

    UniProtKB/TrEMBL
    A0A8M2BB19, F1R5K6
    Related
    ENSDARP00000104138.3, ENSDART00000109894.4
    Conserved Domains (2) summary
    pfam02191
    Location:228 → 472
    OLF; Olfactomedin-like domain
    pfam12308
    Location:52 → 150
    Noelin-1; Neurogenesis glycoprotein
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.