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rbm12bb RNA binding motif protein 12Bb [ Danio rerio (zebrafish) ]

Gene ID: 334496, updated on 12-Sep-2024

Summary

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Official Symbol
rbm12bbprovided by ZNC
Official Full Name
RNA binding motif protein 12Bbprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-6428
See related
Ensembl:ENSDARG00000079717 AllianceGenome:ZFIN:ZDB-GENE-030131-6428
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
rbm12b; fi89g10; zgc:56148; wu:fi89g10; si:ch211-193p21.4
Summary
Predicted to enable RNA binding activity. Predicted to be involved in regulation of RNA splicing. Predicted to be part of ribonucleoprotein complex. Predicted to be active in nucleoplasm. Orthologous to human RBM12B (RNA binding motif protein 12B). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See rbm12bb in Genome Data Viewer
Location:
chromosome: 16
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (16232621..16237860, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (16324644..16329883, complement)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene uridine phosphorylase 1 Neighboring gene granulito Neighboring gene uncharacterized LOC110438014 Neighboring gene SET domain containing 2, histone lysine methyltransferase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Global identification of SMAD2 target genes reveals a role for multiple co-regulatory factors in zebrafish early gastrulas. Liu Z, et al. J Biol Chem, 2011 Aug 12. PMID 21669877, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of RNA splicing IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of ribonucleoprotein complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
RNA binding motif protein 12Bb
Names
RNA binding motif protein 12B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001290140.1 → NP_001277069.1  RNA binding motif protein 12Bb

    Status: VALIDATED

    Source sequence(s)
    BX321920
    UniProtKB/TrEMBL
    A0A8M1P6I4, E7F6E2
    Related
    ENSDARP00000097607.3, ENSDART00000111912.4
    Conserved Domains (5) summary
    COG0724
    Location:521 → 682
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12515
    Location:609 → 683
    RRM5_RBM12_like; RNA recognition motif 5 in RNA-binding protein RBM12, RBM12B and similar proteins
    cd12744
    Location:2 → 80
    RRM1_RBM12B; RNA recognition motif 1 in RNA-binding protein 12B (RBM12B) and similar proteins
    cd12746
    Location:157 → 234
    RRM2_RBM12B; RNA recognition motif 2 in RNA-binding protein 12B (RBM12B) and similar proteins
    cl17169
    Location:275 → 355
    RRM_SF; RNA recognition motif (RRM) superfamily

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    16232621..16237860 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_199905.1: Suppressed sequence

    Description
    NM_199905.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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