ap2b1 adaptor related protein complex 2 subunit beta 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ap2b1provided by ZNC
Official Full Name: adaptor related protein complex 2 subunit beta 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-6564
See related: Ensembl:ENSDARG00000035152 AllianceGenome:ZFIN:ZDB-GENE-030131-6564
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fa16e07; zgc:55659; wu:fa16c06; wu:fa16e07; wu:fc18c08
Summary: Predicted to enable clathrin binding activity. Predicted to be involved in vesicle-mediated transport. Predicted to act upstream of or within intracellular protein transport. Predicted to be located in endomembrane system and membrane. Predicted to be part of clathrin adaptor complex. Orthologous to human AP2B1 (adaptor related protein complex 2 subunit beta 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 22

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	5	NC_007116.7 (61657707..61724086)
105	previous assembly	GRCz10 (GCF_000002035.5)	5	NC_007116.6 (60973012..61039365)

Chromosome 5 - NC_007116.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables clathrin binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in animal organ development	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within intracellular protein transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein transport	IEA Inferred from Electronic Annotation more info
involved_in vesicle-mediated transport	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within vesicle-mediated transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of clathrin adaptor complex	IEA Inferred from Electronic Annotation more info
located_in endomembrane system	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
part_of membrane coat	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: AP-2 complex subunit beta

Names: adaptor-related protein complex 2, beta 1 subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_199919.2 → NP_956213.2 AP-2 complex subunit beta

See identical proteins and their annotated locations for NP_956213.2

Status: PROVISIONAL

Source sequence(s)

BC066566

UniProtKB/TrEMBL

A0A0R4IC49, A0A8M1PAE5, B0R152, Q6NYJ9

Related

ENSDARP00000132587.2, ENSDART00000171248.2

Conserved Domains (5) summary

smart00809
Location:731 → 831

Alpha_adaptinC2; Adaptin C-terminal domain

smart01020
Location:840 → 950

B2-adapt-app_C; Beta2-adaptin appendage, C-terminal sub-domain

pfam01602
Location:11 → 534

Adaptin_N; Adaptin N terminal region

pfam12717
Location:99 → 268

Cnd1; non-SMC mitotic condensation complex subunit 1

sd00044
Location:51 → 75

HEAT; HEAT repeat [structural motif]