U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

lrrfip2 leucine rich repeat (in FLII) interacting protein 2 [ Danio rerio (zebrafish) ]

Gene ID: 335838, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
lrrfip2provided by ZNC
Official Full Name
leucine rich repeat (in FLII) interacting protein 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-7781
See related
Ensembl:ENSDARG00000010400 AllianceGenome:ZFIN:ZDB-GENE-030131-7781
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:63771; wu:fj34c02; zgc:113956
Summary
Predicted to act upstream of or within regulation of DNA-templated transcription. Is expressed in hatching gland; myotome; pectoral fin; and somite. Orthologous to human LRRFIP2 (LRR binding FLII interacting protein 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See lrrfip2 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
28
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (42621205..42674001, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (42495145..42548189, complement)

Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137487438 Neighboring gene mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) Neighboring gene mitochondrial ribosomal protein L14 Neighboring gene calpain 1, (mu/I) large subunit a

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Dynamics of zebrafish fin regeneration using a pulsed SILAC approach. Nolte H, et al. Proteomics, 2015 Feb. PMID 25504979
  2. Rbfox-regulated alternative splicing is critical for zebrafish cardiac and skeletal muscle functions. Gallagher TL, et al. Dev Biol, 2011 Nov 15. PMID 21925157, Free PMC Article
  3. Coherent but overlapping expression of microRNAs and their targets during vertebrate development. Shkumatava A, et al. Genes Dev, 2009 Feb 15. PMID 19240133, Free PMC Article
  4. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  5. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • MGC63771, MGC113956

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
leucine-rich repeat flightless-interacting protein 2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001034974.4 → NP_001030146.2  leucine-rich repeat flightless-interacting protein 2 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    BX936318, EH115383, EH496054, EH577418
    UniProtKB/TrEMBL
    A0A0R4IMS4, A0A8M1N7T5
    Related
    ENSDARP00000135819.1, ENSDART00000169083.2
    Conserved Domains (1) summary
    pfam09738
    Location:50 → 354
    DUF2051; Double stranded RNA binding protein (DUF2051)

  2. NM_199479.3 → NP_955773.1  leucine-rich repeat flightless-interacting protein 2 isoform 2

    See identical proteins and their annotated locations for NP_955773.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an exon in the coding region compared to variant 1. The resulting protein (isoform 2) is shorter but has the same N- and C-termini compared to isoform 1.
    Source sequence(s)
    BX936318, EH115383, EH496054, EH577418
    UniProtKB/TrEMBL
    Q6PGV0, Q6TEN2
    Related
    ENSDARP00000090511.4, ENSDART00000099738.6
    Conserved Domains (1) summary
    pfam09738
    Location:50 → 330
    DUF2051; Double stranded RNA binding protein (DUF2051)

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007124.7 Reference GRCz11 Primary Assembly

    Range
    42621205..42674001 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021480537.2 → XP_021336212.1  leucine-rich repeat flightless-interacting protein 2 isoform X13

    UniProtKB/TrEMBL
    A0A8M9PXQ2
    Conserved Domains (2) summary
    pfam04111
    Location:344 → 439
    APG6; Autophagy protein Apg6
    pfam09738
    Location:50 → 364
    LRRFIP; LRRFIP family

  2. XM_005169524.5 → XP_005169581.1  leucine-rich repeat flightless-interacting protein 2 isoform X11

    UniProtKB/TrEMBL
    A0A8M2BHE2
    Conserved Domains (1) summary
    pfam09738
    Location:50 → 395
    DUF2051; Double stranded RNA binding protein (DUF2051)

  3. XM_021480536.2 → XP_021336211.1  leucine-rich repeat flightless-interacting protein 2 isoform X12

    UniProtKB/TrEMBL
    A0A8M9QJK5
    Conserved Domains (2) summary
    pfam04111
    Location:368 → 463
    APG6; Autophagy protein Apg6
    pfam09738
    Location:50 → 388
    LRRFIP; LRRFIP family

  4. XM_005169523.5 → XP_005169580.1  leucine-rich repeat flightless-interacting protein 2 isoform X10

    UniProtKB/TrEMBL
    A0A8M2BGV2
    Conserved Domains (1) summary
    pfam09738
    Location:50 → 419
    DUF2051; Double stranded RNA binding protein (DUF2051)

  5. XM_021480535.2 → XP_021336210.1  leucine-rich repeat flightless-interacting protein 2 isoform X9

    UniProtKB/TrEMBL
    A0A8M9QNB1
    Conserved Domains (2) summary
    pfam09738
    Location:279 → 560
    LRRFIP; LRRFIP family
    cl26309
    Location:363 → 635
    MscS_TM; Mechanosensitive ion channel inner membrane domain 1

  6. XM_021480533.2 → XP_021336208.1  leucine-rich repeat flightless-interacting protein 2 isoform X5

    UniProtKB/TrEMBL
    A0A8M9Q9K7
    Conserved Domains (2) summary
    pfam09738
    Location:344 → 625
    LRRFIP; LRRFIP family
    cl26309
    Location:428 → 700
    MscS_TM; Mechanosensitive ion channel inner membrane domain 1

  7. XM_068224934.1 → XP_068081035.1  leucine-rich repeat flightless-interacting protein 2 isoform X2

  8. XM_017358706.3 → XP_017214195.1  leucine-rich repeat flightless-interacting protein 2 isoform X8

    UniProtKB/TrEMBL
    A0A8M6Z279

  9. XM_021480534.2 → XP_021336209.1  leucine-rich repeat flightless-interacting protein 2 isoform X6

    UniProtKB/TrEMBL
    A0A8M9QF96
    Conserved Domains (2) summary
    pfam04111
    Location:601 → 696
    APG6; Autophagy protein Apg6
    pfam09738
    Location:317 → 621
    LRRFIP; LRRFIP family

  10. XM_017358705.3 → XP_017214194.1  leucine-rich repeat flightless-interacting protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8M6Z935

  11. XM_005169520.5 → XP_005169577.1  leucine-rich repeat flightless-interacting protein 2 isoform X7

    UniProtKB/TrEMBL
    A0A8M2BGW9
    Conserved Domains (3) summary
    pfam09738
    Location:395 → 611
    DUF2051; Double stranded RNA binding protein (DUF2051)
    pfam12777
    Location:574 → 659
    MT; Microtubule-binding stalk of dynein motor
    cl23765
    Location:379 → 475
    iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits

  12. XM_021480532.2 → XP_021336207.1  leucine-rich repeat flightless-interacting protein 2 isoform X4

    UniProtKB/TrEMBL
    A0A8M9PXP5
    Conserved Domains (2) summary
    pfam04111
    Location:625 → 720
    APG6; Autophagy protein Apg6
    pfam09738
    Location:395 → 645
    LRRFIP; LRRFIP family

  13. XM_005169517.5 → XP_005169574.1  leucine-rich repeat flightless-interacting protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8M2BGT5
    Conserved Domains (1) summary
    pfam09738
    Location:395 → 676
    DUF2051; Double stranded RNA binding protein (DUF2051)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools