arf6a ADP-ribosylation factor 6a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: arf6aprovided by ZNC
Official Full Name: ADP-ribosylation factor 6aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-8007
See related: Ensembl:ENSDARG00000101626 AllianceGenome:ZFIN:ZDB-GENE-030131-8007
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: arf6; zgc:77665; wu:fj46d09
Summary: Predicted to enable GTP binding activity. Acts upstream of or within intrahepatic bile duct development; regulation of apoptotic process; and spinal cord development. Predicted to be located in Flemming body; cleavage furrow; and filopodium membrane. Predicted to be active in cytoplasmic vesicle; plasma membrane; and ruffle. Is expressed in intestinal bulb; liver; and pancreas. Orthologous to human ARF6 (ADP ribosylation factor 6). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 20

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	20	NC_007131.7 (54196542..54198130, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	20	NC_007131.6 (54525723..54527311)

Chromosome 20 - NC_007131.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

G40257 (e-PCR)
- UniSTS:44561

fj46d09.x1 (e-PCR)
- UniSTS:199401

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables G protein activity	IEA Inferred from Electronic Annotation more info
enables GTP binding	IBA Inferred from Biological aspect of Ancestor more info
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables GTPase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in intracellular protein transport	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within intrahepatic bile duct development	IGI Inferred from Genetic Interaction more info	PubMed
involved_in protein localization to endosome	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of dendritic spine development	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within regulation of neuron apoptotic process	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within regulation of oligodendrocyte apoptotic process	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within spinal cord development	IGI Inferred from Genetic Interaction more info	PubMed
involved_in vesicle-mediated transport	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in Flemming body	IEA Inferred from Electronic Annotation more info
located_in cleavage furrow	IEA Inferred from Electronic Annotation more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in endocytic vesicle	IBA Inferred from Biological aspect of Ancestor more info
located_in filopodium membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in recycling endosome membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in ruffle	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: ADP-ribosylation factor 6a

Names: ADP-ribosylation factor 6

NP_956287.1

EC 3.6.5.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.