U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

abcf2a ATP-binding cassette, sub-family F (GCN20), member 2a [ Danio rerio (zebrafish) ]

Gene ID: 336770, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
abcf2aprovided by ZNC
Official Full Name
ATP-binding cassette, sub-family F (GCN20), member 2aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-8714
See related
Ensembl:ENSDARG00000038785 AllianceGenome:ZFIN:ZDB-GENE-030131-8714
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
abcf2; wu:fb04f06; wu:fc74f03; wu:fd58d07
Summary
Predicted to enable ATP binding activity. Is expressed in neuromast. Orthologous to several human genes including ABCF2 (ATP binding cassette subfamily F member 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See abcf2a in Genome Data Viewer
Location:
chromosome: 2
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (32505554..32513545, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (32522336..32530327, complement)

Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene tetratricopeptide repeat domain 19 Neighboring gene Fas apoptotic inhibitory molecule 2a Neighboring gene SWI/SNF related BAF chromatin remodeling complex subunit D3a Neighboring gene transmembrane and ubiquitin-like domain containing 1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Management of Hypercholesterolemia Through Dietary ß-glucans-Insights From a Zebrafish Model. Gora AH, et al. Front Nutr, 2021. PMID 35096942, Free PMC Article
  2. Identification and expression analysis of kcnh2 genes in the zebrafish. Leong IU, et al. Biochem Biophys Res Commun, 2010 Jun 11. PMID 20438705
  3. Identification of differentially expressed genes between cloned and zygote-developing zebrafish (Danio rerio) embryos at the dome stage using suppression subtractive hybridization. Luo D, et al. Biol Reprod, 2009 Apr. PMID 19092113
  4. Evolution of the vertebrate ABC gene family: analysis of gene birth and death. Annilo T, et al. Genomics, 2006 Jul. PMID 16631343
  5. Evolution of the ATP-binding cassette (ABC) transporter superfamily in vertebrates. Dean M, et al. Annu Rev Genomics Hum Genet, 2005. PMID 16124856

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
ATP-binding cassette sub-family F member 2a
Names
ATP-binding cassette, sub-family F (GCN20), member 2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_201315.2 → NP_958472.2  ATP-binding cassette sub-family F member 2a

    Status: VALIDATED

    Source sequence(s)
    BE557347, BI709967, BX323804, CT713297, EH556650, EH577748
    UniProtKB/TrEMBL
    A0A0R4IBA2, A0A8N7V050, F1QZ64
    Related
    ENSDARP00000056639.2, ENSDART00000056640.4
    Conserved Domains (3) summary
    cd03221
    Location:83 → 299
    ABCF_EF-3; ATP-binding cassette domain of elongation factor 3, subfamily F
    COG0488
    Location:80 → 600
    Uup; ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]
    pfam12848
    Location:293 → 363
    ABC_tran_Xtn; ABC transporter

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007113.7 Reference GRCz11 Primary Assembly

    Range
    32505554..32513545 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools