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zgc:153867 zgc:153867 [ Danio rerio (zebrafish) ]

Gene ID: 337226, updated on 28-Oct-2024

Summary

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Official Symbol
zgc:153867provided by ZNC
Official Full Name
zgc:153867provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-9170
See related
Ensembl:ENSDARG00000033738 AllianceGenome:ZFIN:ZDB-GENE-030131-9170
Gene type
protein coding
RefSeq status
PREDICTED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
MLC3SM; fb02e09; wu:fa98e09; wu:fb02e09; hm:zehn1575
Summary
Predicted to be a structural constituent of muscle. Predicted to be part of myosin II complex. Orthologous to human MYL6 (myosin light chain 6). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
all
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Genomic context

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See zgc:153867 in Genome Data Viewer
Location:
chromosome: 23
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (28374435..28388513)
105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (28448069..28461972)

Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene baculoviral IAP repeat containing 5b Neighboring gene neuronal differentiation 4 Neighboring gene uncharacterized LOC137489133 Neighboring gene complement component 1, q subcomponent-like 4 Neighboring gene uncharacterized LOC101882861

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Wnt1 and wnt10b function redundantly at the zebrafish midbrain-hindbrain boundary. Lekven AC, et al. Dev Biol, 2003 Feb 15. PMID 12591239
  2. Depletion of zebrafish essential and regulatory myosin light chains reduces cardiac function through distinct mechanisms. Chen Z, et al. Cardiovasc Res, 2008 Jul 1. PMID 18343897, Free PMC Article
  3. Spermidine, but not spermine, is essential for pigment pattern formation in zebrafish. Frohnhöfer HG, et al. Biol Open, 2016 Jun 15. PMID 27215328, Free PMC Article
  4. The proteomic study on cellular responses of the testes of zebrafish (Danio rerio) exposed to microcystin-RR. Zhao S, et al. Proteomics, 2012 Jan. PMID 22140076
  5. Comparative transcriptome analyses indicate molecular homology of zebrafish swimbladder and mammalian lung. Zheng W, et al. PLoS One, 2011. PMID 21887364, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of muscle IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of myosin II complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC337226

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_213638.1 → NP_998803.1  uncharacterized protein LOC337226

    See identical proteins and their annotated locations for NP_998803.1

    Status: PREDICTED

    Source sequence(s)
    AY391442
    UniProtKB/TrEMBL
    B2GQW5, F6PB68, Q6TNS5
    Related
    ENSDARP00000025083.7, ENSDART00000014983.9
    Conserved Domains (3) summary
    PTZ00184
    Location:5 → 150
    PTZ00184; calmodulin; Provisional
    smart00054
    Location:11 → 39
    EFh; EF-hand, calcium binding motif
    cd00051
    Location:88 → 149
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007134.7 Reference GRCz11 Primary Assembly

    Range
    28374435..28388513
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021469754.2 → XP_021325429.1  uncharacterized protein LOC337226 isoform X1

    UniProtKB/TrEMBL
    A0A8M9PKL9
    Related
    ENSDARP00000120093.1, ENSDART00000144240.3
    Conserved Domains (1) summary
    cl25352
    Location:60 → 208
    EFh_PEF; The penta-EF hand (PEF) family

  2. XM_021469755.2 → XP_021325430.1  uncharacterized protein LOC337226 isoform X2

    UniProtKB/TrEMBL
    A0A8M9PWC9
    Conserved Domains (1) summary
    cl25352
    Location:60 → 208
    EFh_PEF; The penta-EF hand (PEF) family

  3. XM_017353524.3 → XP_017209013.1  uncharacterized protein LOC337226 isoform X4

    UniProtKB/TrEMBL
    A0A8M6Z3P2

  4. XM_005162231.4 → XP_005162288.3  uncharacterized protein LOC337226 isoform X3

    UniProtKB/TrEMBL
    A0A8M2B9A6
    Conserved Domains (1) summary
    cl25352
    Location:51 → 196
    EFh_PEF; The penta-EF hand (PEF) family

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018395155.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    342967..354077
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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