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mchr1b melanin-concentrating hormone receptor 1b [ Danio rerio (zebrafish) ]

Gene ID: 353180, updated on 28-Oct-2024

Summary

Official Symbol
mchr1bprovided by ZNC
Official Full Name
melanin-concentrating hormone receptor 1bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030502-5
See related
AllianceGenome:ZFIN:ZDB-GENE-030502-5
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
gpr24b
Summary
Predicted to enable G protein-coupled receptor activity and neuropeptide binding activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in neuron projection and plasma membrane. Is expressed in brain. Human ortholog(s) of this gene implicated in morbid obesity. Orthologous to human MCHR1 (melanin concentrating hormone receptor 1). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
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Genomic context

See mchr1b in Genome Data Viewer
Location:
chromosome: 3
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (25501301..25510091)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (25370756..25379504)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene transfer RNA serine (anticodon AGA) Neighboring gene growth factor receptor-bound protein 2b Neighboring gene ubiquitin specific peptidase 43b Neighboring gene uncharacterized LOC101886214 Neighboring gene uncharacterized LOC137490596

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables melanin-concentrating hormone receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables neuropeptide binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in neuropeptide signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within neuropeptide signaling pathway IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in neuron projection IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
melanin-concentrating hormone receptor 1; melanin-concentrating hormone receptor 1b
Names
G protein-coupled receptor 24b

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    25501301..25510091
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_687321.8XP_692413.3  melanin-concentrating hormone receptor 1

    UniProtKB/TrEMBL
    A0A8N7TF54
    Conserved Domains (2) summary
    pfam00001
    Location:75329
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:69341
    7tm_4; Olfactory receptor